Diagnostic criteria and research progress on lung allograft pathology / 器官移植
Organ Transplantation
; (6): 19-2022.
Article
em Zh
| WPRIM
| ID: wpr-907028
Biblioteca responsável:
WPRO
ABSTRACT
In recent years, the quantity of lung transplantation has been gradually increased in China along with the accumulation of surgical techniques and postoperative management experience of lung transplantation. Multiple lung allograft complications may occur after lung transplantation, mainly including primary graft dysfunction (PGD) caused by ischemia-reperfusion injury (IRI) of the lung allograft, acute and chronic rejection, opportunistic infection or lymphoproliferative disorder of lymphoid tissues induced by the decrease of host immunity due to postoperative use of immunosuppressants, etc. The diagnosis of complications after lung transplantation mainly relies on biopsy of the lung allograft. In this article, the brief history of lung allograft pathology, main approaches and pathological processing techniques of lung allograft biopsy, major complications after lung transplantation and pathological diagnostic criteria were elucidated, aiming to provide reference for targeted management of these complications in clinical practice.
Chronic obstructive pulmonary disease; Cystic fibrosis; Acute cellular rejection (ACR); Antibody-mediated rejection (AMR); T cell-mediated rejection (TCMR); Transbronchial lung biopsy (TBLB); Transbronchial cryobiopsy (TBCB); Bronchoalveolar lavage; Obliterative bronchiolitis (OB); Transplant-associated vasculopathy (TAV)
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Organ Transplantation
Ano de publicação:
2022
Tipo de documento:
Article