The research progress on the basic characteristics and metabolic regulation of α1-acid glycoprotein / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 6-11, 2022.
Article
em Zh
| WPRIM
| ID: wpr-907147
Biblioteca responsável:
WPRO
ABSTRACT
Metabolic homeostasis is a basic function necessary for the survival of the organism. α1-acid glycoprotein (AGP) is an acute phase protein with a glycosylation degree of up to 45%. It has high affinity and low capacity. Although the biological role of AGP is not fully understood, it has been proven that it can regulate immunity and metabolism, and play an important role in transporting drugs and maintaining capillary barrier function. In this review, the structural characteristics, biochemical characteristics and the regulation of AGP expression were reviewed, with emphasis on the regulatory role of AGP in metabolism, suggesting that AGP may be a potential key factor in metabolic pathways, which provides a new research direction for metabolic diseases.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Pharmaceutical Practice
Ano de publicação:
2022
Tipo de documento:
Article