Specialized proresolving lipid mediators and eye diseases / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology
; (12): 649-654, 2021.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-908566
Biblioteca responsável:
WPRO
ABSTRACT
Novel endogenous lipid-mediated molecules including lipoxins, resolvins, protectins, and maresin families are discovered recently and are collectively called specialized proresolving lipid mediators (SPMs). SPMs have the potential to promote the resolution of inflammation, the elimination of pathogen, and the restoration of homeostasis.Meanwhile, SPMs also have the function of apoptosis inhibition, wound healing, and neuroprotection.SPMs play an important role in the treatment of many eye diseases, such as corneal inflammatory diseases, dry eye, uveitis, retinal and choroidal neovascularization diseases, etc.In this article, the mechanisms involving the role of SPMs in the occurrence and progress of eye diseases were reviewed to provide a general new basis for the future development of new ophthalmic drugs.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Experimental Ophthalmology
Ano de publicação:
2021
Tipo de documento:
Artigo