An Open Label, Multi-center Clinical Trial of Topical 5% Minoxidil Solution for the Treatment of Male Androgenetic Alopecia (A Phase IV Study) / 대한피부과학회지
Korean Journal of Dermatology
; : 295-302, 2009.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-90894
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Topical 5% minoxidil solution stimulates new hair growth and it helps stop the loss of hair on individuals with androgenetic alopecia (AGA).OBJECTIVE:
We wanted to assess the efficacy and safety of topical 5% minoxidil solution for treating Korean men with AGA.METHODS:
This was a 24-week, open label, clinical trial that was conducted at 14 university dermatologic centers nationwide throughout South Korea as a multicenter study of the Korean Hair Research Society. The eligible subjects for this study were 18- to 65 year-old men with androgenetic alopecia, as defined by the Norwood scale as type III vertex, IV and IVA. A total of 175 men (20~62 years old) with AGA applied topical 5% minoxidil solution twice daily. Efficacy was evaluated by 1) the total hair count per 1 cm2 and 2) the mean hair diameter and 3) the patient assessment and 4) the investigator assessment of the change in scalp coverage and the benefit of treatment.RESULTS:
At week 24 as compared with baseline, there was a statistically significant increase in the total hair counts and the mean hair diameter (p<.0001). Topical 5% minoxidil solution helped improve the investigator and patient assessments. The topical 5% minoxidil solution was well tolerated over a 24-week period.CONCLUSION:
We believe that topical 5% minoxidil solution is a safe and effective drug for Korean men with AGA.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pesquisadores
/
Couro Cabeludo
/
Alopecia
/
República da Coreia
/
Cabelo
/
Minoxidil
Tipo de estudo:
Ensaio clínico controlado
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2009
Tipo de documento:
Artigo