Amphotericin B or its liposome combined with antimony sodium gluconate in the treatment of refractory Kala-azar: a report of 4 cases / 中华地方病学杂志
Chinese Journal of Endemiology
; (12): 670-673, 2021.
Article
em Zh
| WPRIM
| ID: wpr-909075
Biblioteca responsável:
WPRO
ABSTRACT
Objective:To investigate the effect of amphotericin B or its liposomes combined with antimony sodium gluconate (antimonial) in the treatment of refractory Kala-azar.Methods:Four patients with Kala-azar who relapsed or were resistant to antimony after treatment were admitted to the First Hospital of Lanzhou University. The clinical medical records were retrospectively analyzed, including the general information (gender, age, etc), diagnosis and treatment process, clinical manifestations, treatment methods and treatment effect.Results:The clinical symptoms of four patients were relieved after treatment with amphotericin B or its liposomes combined with antimonial. Reexamination of bone marrow smear showed no Leishman-Donovan body. There was no recurrence after six months of follow-up.Conclusion:Amphotericin B or its liposomes combined with antimonial can be used in the treatment of refractory Kala-azar.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endemiology
Ano de publicação:
2021
Tipo de documento:
Article