Exosomal microRNAs: an emerging player in systemic lupus erythematosus / 生理学报
Acta Physiologica Sinica
; (6): 1035-1042, 2021.
Article
em Zh
| WPRIM
| ID: wpr-921308
Biblioteca responsável:
WPRO
ABSTRACT
Exosomes are nanometer-sized membranous extracellular vesicles that can be secreted by almost all types of cells in the body. Exosomes are involved in cell-to-cell communication through autocrine and paracrine forms. Exosomal microRNAs (miRNAs) are stable in plasma, urine and other body fluids, and have various biological functions. They play an irreplaceable role in the occurrence, development, immune regulation of systemic lupus erythematosus (SLE). Recent studies have proposed that exosomal miRNAs have promising application prospects in the pathogenesis, early diagnosis, and treatment of SLE. Therefore, this review aims to introduce the current research progress on exosomal miRNAs in SLE and analyze their potential application value.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Comunicação Celular
/
MicroRNAs
/
Exossomos
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Screening_studies
Limite:
Humans
Idioma:
Zh
Revista:
Acta Physiologica Sinica
Ano de publicação:
2021
Tipo de documento:
Article