Effect of Photodynamic Therapy and Intravitreal Triamcinolone Acetonide on Choroidal Neovascularization in Age-related Macular Degeneration
Journal of the Korean Ophthalmological Society
; : 1321-1327, 2005.
Article
em Ko
| WPRIM
| ID: wpr-92743
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To evaluate the safety and visual outcome of intravitreal triamcinolone acetonide combined with photodynamic therapy for subfoveal choroidal neovascularization in patients with age-related macular degeneration. METHODS: We evaluated 32 eyes of 32 patients with choroidal neovascularization due to age-related macular degeneration. The study group received photodynamic therapy and intravitreal triamcinolone acetonide (combined group), while the control group received photodynamic therapy only (PDT group). RESULTS: Three months after treatment, no difference was detected between the two groups in visual acuity changes (p>0.05), but the leakage in fluorescein angiography and macular edema in optical coherent tomography decreased (p<0.05) in the combined group. The retreatment rate in the combined group (6.0%) after 3 months was lower than that of the PDT group (53.3%). CONCLUSIONS: Photodynamic therapy with intravitreal triamcinolone acetonide to choroidal neovascularization reduced the retreatment rate at 3 months significantly. These results may have been be due to the short-term anti-inflammatory effect of steroids.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Fotoquimioterapia
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Esteroides
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Triancinolona
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Triancinolona Acetonida
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Angiofluoresceinografia
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Acuidade Visual
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Edema Macular
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Corioide
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Retratamento
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Neovascularização de Coroide
Limite:
Humans
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2005
Tipo de documento:
Article