Chemical constituents of cyclic peptides from fibrous roots of Pseudostellaria heterophylla / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 122-126, 2022.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-927918
Biblioteca responsável:
WPRO
ABSTRACT
Four cyclic peptides were isolated from the 75% ethanol extract of the fibrous roots of Pseudostellaria heterophylla by silica gel, Sephadex LH-20 column chromatography, and semi-preparative HPLC. Through mass spectrometry, NMR and other methods, they were identified as pseudostellarin L(1), heterophyllin B(2), pseudostellarin B(3), and pseudostellarin C(4). Among them, compound 1 was a new cyclic peptide, and compounds 2-4 were isolated from the fibrous roots of P. heterophylla for the first time. None of these compounds displayed cytotoxic activities against MCF-7, A549, HCT-116, and SGC-7901 cells.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeos Cíclicos
/
Espectroscopia de Ressonância Magnética
/
Cromatografia Líquida de Alta Pressão
/
Raízes de Plantas
/
Caryophyllaceae
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2022
Tipo de documento:
Artigo