Cytokine storms associated with respiratory virus infection and targeted therapy strategies / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
; (24): 1913-1917, 2021.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-930356
Biblioteca responsável:
WPRO
ABSTRACT
Since December 2019, the novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) infection has broken out worldwide, causing enormous social and economic burdens.Sudden exacerbations in SARS-CoV-2 infected people may be caused by infection-related cytokine storms.The basic state of the body and the strength of the immune response determine the prognosis of SARS-CoV-2.The interaction between proinflammatory factors and anti-inflammatory factors, and continued proinflammatory response cause lung edema, exudation, progression to acute respiratory distress syndrome involving the lung tissues and organs, multi-organ failure, and even death.The efficacy of antiviral therapy alone for immune complications like cytokine storm during viral infection is not ideal, and the targeted therapy of cytokines has become a potentially popular therapeutic strategy.Early identification and appropriate treatment of immune complications contribute to reduce the morbidity and mortality of severe viral infections.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Problema de saúde:
COVID-19
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Applied Clinical Pediatrics
Ano de publicação:
2021
Tipo de documento:
Artigo