Correlation of social support, mental resilience and quality of life in patients with hematologic malignancy / 中华行为医学与脑科学杂志

ABSTRACT

Objective:To understand the quality of life in patients with hematologic malignancy, and to discuss the correlation among quality of life and social support and resilience in the patients, and to analyze the mediating effect of mental resilience.Methods:A total of 284 patients with hematologic malignancy from Affiliated Hospital of Jining Medical University completed social support rate scale(SSRS), Connor-Davidson resilience scale(CD-RISC) and European Organization for research and treatment of cancer quality of life questionnaires-core 30(EORTC QLQ-C30). SPSS 21.0 was used for descriptive statistics, single sample t-test, Pearson correlation analysis and SPSS macro program PROCESS v 3.4 was used for testing the mediating effect. Results:The general health level of quality of life in patients with hematologic malignancy(52.1±26.4)was significantly lower than the Norwegian norm(75.3)( t=-14.81, P<0.01). Social support was significantly positively correlated with resilience and quality of life( r=0.76, 0.31, P<0.01), and resilience was positively correlated with quality of life( r=0.45, P<0.01). Mental resilience played a partial mediating role between social support and quality of life, and the mediating effect accounted for 61% of the total effect. Conclusion:Mental resilience can be used as a mediating variable for social support which can affect quality of life.Improving the mental resilience and social support in patients with hematologic malignancy can effectively improve their quality of life.