Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro / 中华烧伤杂志
Chinese Journal of Burns
; (6): 195-200, 2022.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-935995
Biblioteca responsável:
WPRO
ABSTRACT
The damage of sweat glands in patients with extensive deep burns results in the loss of thermoregulation, which seriously affects the quality of life of patients. At present, there are many researches on the repair of sweat gland function, but the mechanism of human sweat gland development has not been fully clarified. More and more studies have shown that the cascaded pathways of Wnt/β-catenin, ecto- dysplasin A/ectodysplasin A receptor/nuclear factor-κB, sonic hedgehog, and forkhead box transcription factor jointly affect the development of sweat glands, and it has been reported that the cascaded signaling pathways can be used to achieve the reconstruction of sweat adenoid cells in vitro. This article reviews the signaling pathways that affect the development of sweat glands and their involvement in the reconstruction of sweat adenoid cells in vitro.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Qualidade de Vida
/
Suor
/
Glândulas Sudoríparas
/
Transdução de Sinais
/
Tonsila Faríngea
/
Proteínas Hedgehog
Aspecto:
Preferência do paciente
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Burns
Ano de publicação:
2022
Tipo de documento:
Artigo