Progress of tyrosine kinase inhibitor resistance in chronic myeloid leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 374-377, 2022.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-953973
Biblioteca responsável:
WPRO
ABSTRACT
Chronic myeloid leukemia (CML) is a malignant tumor formed by clonal proliferation of bone marrow hematopoietic stem cells. With the improvement of disease awareness and the introduction of new drugs, more than 90% of CML patients can achieve long-term survival. However, a few patients still show drug resistance. This article reviews the mechanism of drug resistance in CML patients treated with tyrosine kinase inhibitor (TKI) and the characteristics of ABL kinase region mutation.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Leukemia & Lymphoma
Ano de publicação:
2022
Tipo de documento:
Artigo