Comparison of Three Third-generation Anti-HCV Enzyme Immunoassay Tests / 영남의대학술지
Yeungnam University Journal of Medicine
; : 143-150, 1998.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-96003
Biblioteca responsável:
WPRO
ABSTRACT
The aim of this study was to evaluate domestic enzyme immunoassay(EIA) kit ?LG HCD 3.0?(LG) for the detection of antibody to hepatitis C virus(anti-HCV) in comparision with Axsym HCV version 3.0(Axsym), Cobas Core anti-HCV EIA(Cobas). Cobas kit shows better clear distinction between positive and negative by signal/cutoff ratio(S/C), but it also reveal relatively high false positive rate. The concordance rate of test results between LG and Axsym was 96.2%, between LG and Cobas was 95.5%, and total agreement between three EIA kit was 93.9%. LG were relative poor distinction between positive and negative results, but it could be applied clinically as a screening tool for hepatitis C in general population. The S/C of one false negative result by LG was 0.91, and false positive were less than 4.0, therefore we concluded it is necessary to confirm by immunoblotting assay when S/C were between 0.8 and 4.0.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Hepatite
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Immunoblotting
/
Programas de Rastreamento
/
Técnicas Imunoenzimáticas
/
Hepatite C
/
Hepacivirus
Tipo de estudo:
Estudo de rastreamento
Idioma:
Coreano
Revista:
Yeungnam University Journal of Medicine
Ano de publicação:
1998
Tipo de documento:
Artigo