Research progress on vaccines against human respiratory syncytial virus / 中国生物制品学杂志
Chinese Journal of Biologicals
; (12): 379-2023.
Article
em Zh
| WPRIM
| ID: wpr-976148
Biblioteca responsável:
WPRO
ABSTRACT
@#Human respiratory syncytial virus(hRSV)is one of the main pathogens that cause lower respiratory tract infection in infants and the elderly.hRSV genome contains 10 genes with a full length of 15 222 bp,encoding 11 proteins(9structural proteins and 2 non-structural proteins).Different proteins play different roles in the pathogenesis of hRSV.With the in-depth research on the biological and structural characteristics of hRSV,various types of hRSV vaccines have been developed,making rapid progress.For example,hRSV attenuated live vaccine hRSV ?NS2/?1313/I1314L has entered Phase II clinical trial,and hRSV subunit protein vaccine Pre-F-GCN4t has entered Phase III clinical trial.In this paper,the biological characteristics of hRSV and the types of hRSV vaccines with rapid progress are reviewed so as to provide a reference for the development of hRSV vaccines in China.
Buscar no Google
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Biologicals
Ano de publicação:
2023
Tipo de documento:
Article