Advances in Molecular Targeted Ultrasound Contrast Agents / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 298-302, 2023.
Article
em Zh
| WPRIM
| ID: wpr-981267
Biblioteca responsável:
WPRO
ABSTRACT
In real-time ultrasound,molecular targeted contrast agent is introduced into the blood circulation through peripheral intravenous injection to enhance the imaging signal of target lesions after binding to the corresponding intravascular receptors,which can realize early diagnosis,staging of diseases,assessment of treatment response,and targeted treatment.In addition,molecular targeted ultrasound contrast agents provide a platform for the delivery of drugs and genes via microbubbles,and nanoscale contrast agents can be infiltrated through vascular endothelium into the interstitial space of the lesion for imaging or treatment.The available studies of molecular targeted ultrasound contrast agents mainly focus on the preclinical trials.Some clinical trials have been conducted in humans and preliminarily confirm the safety and feasibility of targeted ultrasound contrast agents.The molecular targeted ultrasound contrast agents enjoy a broad prospect in clinical application.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Diagnóstico por Imagem
/
Ultrassonografia
/
Meios de Contraste
/
Terapia de Alvo Molecular
Limite:
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2023
Tipo de documento:
Article