Ion-pair solid-phase extraction (SPE) and HPLC analysis of paraquat in biological sample / 法医学杂志

ABSTRACT

OBJECTIVE@#To establish an HPLC method for the determination of Paraquat in biological samples.@*METHODS@#Paraquat in biological samples was extracted by C18 columns which were pre-treated with cetyl-trimethyl ammonium bromide (CTAB) and soudium dodecyl sulphate (SDS), and analysed by HPLC/DAD.@*RESULTS@#The detection limit of the method was 1 ng x mL(-1), and the average recoveries were 81%-94%.@*CONCLUSION@#The method can be used to analysis of paraquat in biological samples.