Determination of methamphetamine in whole blood by capillary zone electrophoresis after solid phase extraction / 法医学杂志

ABSTRACT

OBJECTIVE@#To develop a specific CZE method for the determination of methamphetamine in whole blood after solid phase extraction.@*METHODS@#With the doxapram as internal standard, Oasis column was used to extract drugs from whole blood and the sample was analysized by CZE.@*RESULTS@#The method showed excellent linearity and the linear correlation coefficient was 0.994. The relative standard deviation for between-day and within-day were 5.31% and 2.22%, respectively.@*CONCLUSION@#The method is effective, simple, reliable and has been used in the determination of methamphetamine in whole blood.