Gitelman's Syndrome Associated with Chondrocalcinosis
Journal of Rheumatic Diseases
; : 266-270, 2016.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-98405
Biblioteca responsável:
WPRO
ABSTRACT
Gitelman's syndrome (GS), a hereditary disease characterized by hypokalemia, hypomagnesemia, and hypocalciuria, is a salt-losing renal tubulopathy. Herein, we describe a case of a 28-year-old woman diagnosed with atypical GS accompanying chondrocalcinosis. One year ago, she presented with vomiting, hypokalemic metabolic alkalosis, and hypocalciuria, and was tested by diuretic challenge test. As a result, she was diagnosed with atypical GS with normomagnesemia and treated with spironolactone and potassium supplementation. Meanwhile, acute arthritis of the right 1st metatarsophalangeal joint occurred. On the radiographies of the knees, chondrocalcinosis was observed. To the best of our knowledge, this is the first report in Korea of GS with chondrocalcinosis. Antialdosterone therapy or magnesium supplementation is effective in preventing the progression of chondrocalcinosis; thus, early diagnosis and treatment of GS are important.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Potássio
/
Artrite
/
Espironolactona
/
Vômito
/
Condrocalcinose
/
Diagnóstico Precoce
/
Alcalose
/
Síndrome de Gitelman
/
Doenças Genéticas Inatas
/
Hipopotassemia
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Rheumatic Diseases
Ano de publicação:
2016
Tipo de documento:
Artigo