Analysis of the Distribution of Total Phosphine and the Characteristics of Phosphine Poisoning in 29 Victims / 法医学杂志
Journal of Forensic Medicine
; (6): 254-257, 2022.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-984117
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVES@#To study the distribution of total phosphine in phosphine poisoning victims and summarize the characteristics of phosphine poisoning cases.@*METHODS@#The phosphine and its metabolites in the biological samples of 29 victims in 16 phosphine poisoning cases were qualified and quantified by headspace gas chromatography-mass spectrometry.@*RESULTS@#Five victims among 29 were poisoned by ingestion of aluminium phosphide and 24 by inhalation of phosphine gas. Phosphine metabolites were detected in the biological samples of 23 victims, and the concentrations of total phosphine in blood ranged 0.5-34.0 μg/mL. The total concentration of phosphine in liver tissue was up to 71.0 μg/g. Phosphine was not detected in the blood of the other six survived victims, which may be related to the small amount of phosphine exposure and the delay in blood sampling.@*CONCLUSIONS@#The total concentration of phosphine in blood and tissues caused by aluminum phosphine ingestion is higher than that caused by phosphine gas inhalation. The death cases of phosphine inhalation are characterized by long exposure time, repeated exposures and age susceptibility.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Zoonoses
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fosfinas
/
Intoxicação
/
Compostos de Alumínio
/
Fígado
/
Cromatografia Gasosa-Espectrometria de Massas
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Forensic Medicine
Ano de publicação:
2022
Tipo de documento:
Artigo