Role of CCAAT/enhancer binding protein β in acute cerebral ischemia / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 792-796, 2022.
Article
em Zh
| WPRIM
| ID: wpr-989157
Biblioteca responsável:
WPRO
ABSTRACT
CCAAT/enhancer binding protein β (C/EBPβ), a transcriptional factor of the basic-leucine zipper family, can regulate the transcription activity of downstream target genes. After acute cerebral ischemia, the activity of C/EBPβ changes, and participates in the process of cerebral ischemia injury by regulating neuronal apoptosis and inflammation. This article reviews the molecular biological characteristics of C/EBPβ and its expression changes and role in acute cerebral ischemia, providing a basis for developing new neuroprotective drugs for acute cerebral ischemia using C/EBPβ as therapeutic target.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
International Journal of Cerebrovascular Diseases
Ano de publicação:
2022
Tipo de documento:
Article