Clinical Characteristics of Gastroallergic Anisakiasis and Diagnostic Implications of Immunologic Tests
Allergy, Asthma & Immunology Research
; : 228-233, 2014.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-99070
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Recent studies have used the term "gastroallergic anisakiasis" to describe incidental gastrointestinal infection with Anisakis spp. larvae, proposed as a causative agent of food hypersensitivity. However, it is unknown whether this condition represents an independent disease entity distinguishable from acute gastric anisakiasis. To better understand the role of the allergic response in Anisakis infections we examined the clinical and immunological implications of Anisakis-specific IgE.METHODS:
A prospective study was performed in a geographic region where the consumption of raw seafood is common. Case subjects who had been clinically diagnosed with gastroallergic anisakiasis were selected, along with controls who frequently ate raw seafood but had never experienced gastroallergic anisakiasis-like symptoms. Clinical and immunological features were compared based on atopic status, sensitization rates to Anisakis, and serum titer of Anisakis-specific IgE.RESULTS:
Seventeen case subjects and 135 controls were included in this study. The case subjects had experienced gastrointestinal symptoms after raw seafood ingestion, along with additional mucocutaneous, respiratory, or multisystemic symptoms. Case subjects were significantly sensitized to Anisakis excretory-secretory product and crude extract compared with controls (76.5% vs. 19.3%, P17.5 kU/L) were found to be reliable indicators for the diagnosis of gastroallergic anisakiasis.CONCLUSIONS:
Among patients presenting acute gastric anisakiasis-like symptoms, a diagnosis of gastroallergic anisakiasis may be strongly supported by a high Anisakis-specific IgE titer.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Helmintíase
/
Doenças Negligenciadas
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Testes Imunológicos
/
Imunoglobulina E
/
Testes Cutâneos
/
Estudos Prospectivos
/
Anisakis
/
Anisaquíase
/
Alimentos Marinhos
/
Diagnóstico
/
Ingestão de Alimentos
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Humanos
Idioma:
Inglês
Revista:
Allergy, Asthma & Immunology Research
Ano de publicação:
2014
Tipo de documento:
Artigo