A case of autoimmune chronic pancreatitis associated with sjogren's syndrome / 대한내과학회지

ABSTRACT

We report a case of autoimmune chronic pancreatitis associated with Sjogren's syndrome. A 68-year-old man was admitted to the hospital with jaundice. The serum IgG and IgE were elevated and endoscopic retrograde cholangiopancreatography demonstrated an irregular narrowing of the main pancreatic duct and stricture of the distal common bile duct. He complained of dry mouth and dry eyes with a gritty feeling. On physical examination, enlargement of both submandibular glands was noted. Schirmer test revealed positive result and the labial minor salivary gland biopsy showed infiltration of lymphocytes and plasma cells, consistent with Sjogren's syndrome. After one month of oral steroid therapy, the abnormalities in clinical, laboratory and radiological findings of autoimmune chronic pancreatitis were improved markedly. The enlargement of both submandibular glands was improved, too. To our knowledge, this is the first case of autoimmune chronic pancreatitis associated with Sjogren's syndrome in Korea.