ABSTRACT
Background: Toxoplasmosis among the human immunodeficiency virus (HIV) positive individuals with low CD4+cell count can be severe leading to the reactivation of dormant bradyzoites which can lead to morbidity and/or mortality. A reservoir for T. gondii, cat is common around our study area both as pets and stray animals.Study Objective: Is to determine the seroprevalence of T. gondii infection in this community and also to investigate the association between T. gondii infection and CD4 count other risk factors.Methods: Blood specimens were collected from a total of 282 adult HIV positive patients attending a tertiary health facility clinic by systematic sampling and the IgG and IgM levels were detected using the enzyme-linked immunosorbent assay (ELISA) technique. Similarly blood was also collected from 60 healthy blood donors as control group.Results: Out of a total of 282 samples analyzed, 189 were positive for IgG (67%) and 93 were negative. All 282 samples were negative for IgM antibody. A total of 280 had their CD4+cell count above 200cells/microlitre of blood and only 2 recorded less than 200. Nineteen (31.7%) of the 60 blood donors in the control group were positive for IgG and all negative for IgM. The high seroprevalence rate of IgG toxoplasma antibody among HIV positive patients as reported in this study suggests that there should be a high index of suspicion of the recrudescence of toxoplasmosis among HIV and AIDS patients in our environment and possibly elsewhere