ABSTRACT
Objective: To detect Candida species in the urine of patients living with human immuno-deficiency virus (HIV); and correlate the presence of candiduria and CD4 counts. Patients and Methods: The study population consisted of 105 hospitalized patients from the Military and Central Hospitals of Yaounde; who either were HIV positive or already suffering from AIDS. The patients consisted of 63 females (60) and 42 males (40) giving a male to female ratio of 1:1.5. Midstream urine samples were collected from all patients and mycological examination of the centrifuged sediments was done. Patients with CD4 counts 499 lymphocytes/mm3 were a proxy control group. Results: 38 of 105 (36.2) subjects had candiduria. 71of the cases were asympto-matic. The percentage of patients positive versus negative for candiduria increased progressively from stage-A (5) to B (32) to C (63) HIV infection. There was thus a correlation between candiduria and the CDC disease stage. Its presence heralded an advanced immuno-suppressed state of the AIDS patient. Conclusion: In resource-poor communities; where viral copy and CD4 count determination are expensive; candiduria may serve as one of the indicators for anti-retroviral therapy. We recommend routine detection of candiduria in this high-risk group of HIV/AIDS patients
Subject(s)
Candidiasis , HIV Infections , UrineABSTRACT
Une etude retrospective visant a evaluer l'interet du traitement chirurgical de la cryptorchidie a porte sur 123 patients operes a Yaounde pendant une periode de 10 ans allant de 1984 a 1994. L'analyse a revele que 93 patients (75;6 pour cent) avaient ete operes apres l'age de trois ans; au moment ou des alterations histologiques avaient deja compris le pronostic fonctionnel du testicule et augmente le risque de cancerisation. Des resultats comparables dans la litterature montrent l'insuffisance de l'information medicale sur l'age optimal de l'abaissement des testicules cryptorchides. L'etude fait des propositions pour un changement de comportement