Effects Of Monosodium Glutamate (MSG) On The Histological Features Of The Spinal Cord Of Adult Wister Rat

An investigation was carried out on the effects of monosodium glutamate (MSG); a commonly ues food additive; on the spinal cord of adult Wistar rats. Twenty-four adult Wistar rats weighing between 180-250g were divided into four groups of six rats per group. Graduated doses of 6mg; 12mg and 18mg per kilogram body weight were administered orally to the three groups of animals labeled A; B etC. The fourth group served as control and received normal physiological saline. The spinal cord of the animals were dissected out and fixed in 10 formal saline. Spinal cord tissues were processed and stained by the Haematoxyline Eosine method. The results showed increased weight in the experimental animals; which is dose dependent. Histological examination of spinal cord tissues revealed a decreased haematoxylin uptake; which is suggestive of increased metabolic activities. This increase was also observed to be dose dependent. Evidence of cell damage and degeneration within the group also seem to be dose dependent

Traumatic ruptured diaphragm: a clinical diagnostic dilemma

Sequel to a car crash; Chief A; a 52-year old bankerpresented in the Orthopaedic Unit of University of Nigeria Teaching Hospital Enugu with fracture right forearm bones and minor bruises in the abdomen and buttocks. His fractured right forearm was treated surgically and patient was dischharged. A month later; Chief A developed breathlessness and was therefore re-admitted in same hospital where radiological survey including plain chest radiography and tailored barium meal revealed a hitherto clinically Occult rupture left hemi-diaphragm with mediastimal shift to the contra-lateral side. We present this case to highlight the pleomophism of traumatic rupture of diaphragm with emphasis on the causes; clinical presentation; complications and model of progression and different treatment options