Outcome of Directly Observed Therapy Short Course (DOTS) Regimen in a Rural Communicty of the Nigerian Niger Delta

Background: The objective of this retrospective study was to evaluate the outcome of directly observed therapy short course (DOTS) application in a Nigerian rural community.Methods: A retrospective study of all the records of DOTS at the centre from January 2001 to December 2005 was compiled and features such as: age; gender; drugs used; and outcome of treatment (defaulted; cured; died; or developed multidrug resistant-TB) were considered. Also the different personnel and infrastructure at the centre for the programme were also assessed. Results were analysed using Epi Info 6 statistical software; and P values 0.05 were considered significant. Results: Two hundred and seventy four (274) cases of pulmonary TB were registered at the centre during the study period; consisting of 100(36.5) females and 174(63.5) males with a statistically significant gender difference (P0.001). The age range with the highest number of pulmonary tuberculosis cases was 31-40 years (24.8; n=68); and the age range with the lowest number was 71 years and above (1.1; n=3). Treatment outcome showed that 84.7(n=232) completed treatment with cure; 2.5(n=7) developed multidrug resistance at completion of treatment; 5.5(n=15) defaulted; 3.3(n=9) died in the course of treatment; and treatment in 11 people was still ongoing. Conclusion: The outcome of DOTS in the present study was impressive; and the programme should be extended to other rural communities; however; more efforts should be made towards the tracing of defaulters

Genital Mycoplasma Infections among Women in an Urban Community of Northern

Methods: To determine the incidence of genital Mycoplasma infection among females in Jos. High vaginal swab (HVS) and or Endocervical swab (ECS) samples were obtained from 476 females undergoing vaginal examinations along with other females who volunteered to enroll in the study. Samples were processed using standard laboratory procedures for the isolation of Mycoplasma species while information such as age; marital status; occupation and other clinical data were obtained using a questionnaire. The results obtained were analysed using SPSS 11.0 statistical methods and P values = or 0.05 were considered significant. Results: The overall incidence of genital Mycoplasma infection was found to be 29.6(n=141); M. hominis; 12.1(n=57); U. urealyticum 9.4(n=45); mixed infection; 6.7(n=32); and other Mycoplasmas; 1.4(n=7). Majority of the isolates were from those aged 20-35 years old (most sexually active group); 83(n=52) of those who presented with vaginal discharge were infected with Mycoplasma spp. (P 0.05); also; the incidence of infection among the separated/divorce/widowed group was significantly higher than the married group (P

Genital Mycoplasma Infections among Women in an Urban Community of Northern

Methods:To determine the incidence of genital Mycoplasma infection among females in Jos. High vaginal swab (HVS) and or Endocervical swab (ECS) samples were obtained from 476 females undergoing vaginal examinations along with other females who volunteered to enroll in the study. Samples were processed using standard laboratory procedures for the isolation of Mycoplasma species while information such as age; marital status; occupation and other clinical data were obtained using a questionnaire. The results obtained were analysed using SPSS 11.0 statistical methods and P values = or 0.05 were considered significant. Results: The overall incidence of genital Mycoplasma infection was found to be 29.6(n=141); M. hominis; 12.1(n=57); U. urealyticum 9.4(n=45); mixed infection; 6.7(n=32); and other Mycoplasmas; 1.4(n=7). Majority of the isolates were from those aged 20-35 years old (most sexually active group); 83(n=52) of those who presented with vaginal discharge were infected with Mycoplasma spp. (P 0.05); also; the incidence of infection among the separated/divorce/widowed group was significantly higher than the married group (P