ABSTRACT
Objectives: The study aimed to describe the nutritional status and determine the impact of current nutrition intervention strategies on weight changes in adult HIV-infected patients on antiretroviral (ARV) therapy.Design: A descriptive; prospective trial was performed. Setting: The investigation was conducted at ARV roll-out centres in Kimberley; Upington; Kuruman; Prieska and Springbok in the Northern Cape Province of South Africa. Subjects: Adult HIV-infected patients receiving ARV therapy were included in the study.Outcome measures: Each participants's body mass index (BMI) was determined before and after a four-month intervention period of nutritional supplementation with an instant; enriched maize product. Results: Data from 98 patients (mean age 39.7 years; standard deviation 8.9 years) were assessed. Prior to intervention; the median BMI was 20 kg/m2 (range 12.6-29.7 kg/m2); the patients from Kuruman had a greater incidence of underweight compared to the other towns; with a median BMI of 17.9 kg/m2. Of the 87 patients assessed during the final week; 49.4experienced weight gain and 40.2lost weight. Eighteen (20.7) patients gained more than 5of their baseline weight; which was significant. Only eight (9.2) patients lost more than 5of their baseline weight. Twenty-two patients who presented with a BMI 18.5 kg/m2 at baseline had a median weight gain of 1.13 kg during the intervention period; while the group with a BMI 18.5 kg/m2 presented with no change in median weight. Conclusions: Nutritional supplementation; provided according to provincial policy and combined with ARVs; nutritionally benefitted about half of the patients in the ARV programme in the Northern Cape
Subject(s)
Adult , Anti-Retroviral Agents , Dietary Supplements , HIV Infections , Nutritional StatusABSTRACT
Objectives: The study aimed to describe the nutritional status and determine the impact of current nutrition intervention strategies on weight changes in adult HIV-infected patients on antiretroviral (ARV) therapy.Design: A descriptive; prospective trial was performed. Setting: The investigation was conducted at ARV roll-out centres in Kimberley; Upington; Kuruman; Prieska and Springbok in the Northern Cape Province of South Africa. Subjects: Adult HIV-infected patients receiving ARV therapy were included in the study.Outcome measures: Each participants's body mass index (BMI) was determined before and after a four-month intervention period of nutritional supplementation with an instant; enriched maize product. Results: Data from 98 patients (mean age 39.7 years; standard deviation 8.9 years) were assessed. Prior to intervention; the median BMI was 20 kg/m2 (range 12.6-29.7 kg/m2); the patients from Kuruman had a greater incidence of underweight compared to the other towns; with a median BMI of 17.9 kg/m2. Of the 87 patients assessed during the final week; 49.4experienced weight gain and 40.2lost weight. Eighteen (20.7) patients gained more than 5of their baseline weight; which was significant. Only eight (9.2) patients lost more than 5of their baseline weight. Twenty-two patients who presented with a BMI 18.5 kg/m2 at baseline had a median weight gain of 1.13 kg during the intervention period; while the group with a BMI 18.5 kg/m2 presented with no change in median weight. Conclusions: Nutritional supplementation; provided according to provincial policy and combined with ARVs; nutritionally benefitted about half of the patients in the ARV programme in the Northern Cape