ABSTRACT
Background: Hepatitis B is an infectious disease that affects many people worldwide. It may be acute or chronic. Age-specific prevalence varies by geographical region with highest endemicity levels in sub-Saharan Africa and prevalence below 2% in regions such as tropical and central Latin America; North America and Western Europe.Objective: To determine the frequency and characteristics of infected persons with hepatitis B among people from the Lere health department.Participants and method: A 2-month cross-sectional survey was performed in eleven villages in the Lere health department; Chad. At least 100 young people were screened in each village giving a total study population of 1;150 (607 males and 543 females aged = 25 years). Those immunized against hepatitis B were excluded. Studied variables were: age; sex; ethnic group and the results of testing.Results: Hepatitis B tests were positive in 268 cases (23.3%) - 95% of these were from the Moundang ethnic group. Thirty two per cent of boys and 19% of girls aged =15 years were infected; 25% of boys and 13% of girls aged over 15 years were infected.Conclusion: This study shows a high prevalence of hepatitis B in a rural area in Chad. The high proportion among youths aged =15 years indicates that the main way of infection is likely to be the fetal- maternal transmission