1.
Afr. J. Tradit. Complement. Altern. Med. (Online)
; 5(1): 46-50, 2007.
Article
in English
| AIM
| ID: biblio-1256193
ABSTRACT
The activities of total extracts and lupane triterpenes; isolated from the stem bark of Acacia mellifera;were evaluated against Plasmodium berghei strain ANKA in a female Swiss mouse model. Five isolated compounds and the crude extracts were evaluated for antimalarial activity and Quinine hydrochloride was used as a positive control. Only betulin and the methanolic extract produced considerable antimalarial activity in mice infected with P. berghei parasites. This study demonstrated the presence of bioactive agents in Acacia mellifera