Parental piroxicam arthralgia and musculoskeletal conditions of acute malarial [sic] : an open randomised comparison with oral acetylsalicylic acid and paracetamol

An open comparative trial of the toleration and safety of piroxicam; paracetamol and acetylsalicylic acid was conducted in 115 out patients with acute plasmodium falciparum malaria. Patients of both sexes received a single dose of sulfadoxine or pyrimethamine as anti-malarial therapy. Study participants were subsquently randomized to receive standard oral doses of paracetamol; acetylsalicylic; or injectable piroxicam; followed by oral doses of piroxicam; for management of fever; arthralgia and headache associated with acute malaria

An open non-comparative pilot study of the safety and efficacy of oral fluconazole in the treatment of dermatophyte infections in Nigeria

In an non-comparative study to assess the efficacy and safety of oral fluconazole in superficial fungal diseases of the skin; 82 adult Nigerian patients (58 males and 24 females) with clinical and mycological diagnosis of dermatomycoses were enrolled for the trial. Sixty-five patients completed the trial and each of them received a daily dose of 50mg fluconazole for a period of 4 weeks. An overall 90 per cent cure rate was observed in patients with other forms of dermatomycoses and 80 per cent for patients with pityriasis versicolor. The drug was well tolerated by all the patients and very few side effects were noticed