Absence of bacteremia with Mycobacterium avium-intracellulare in Ugandan patients with AIDS

Disseminated infection with Mycobacterium avium-intracellulare is the most common systemic bacterial infection in American patients with the acquired immunodeficiency syndrome. Blood cultures for mycobacteria were obtained from 50 severely ill Ugandan patients fulfilling the World Health Organization criteria for AIDS and considered late in the course of their illness; 98pc had antibody to HIV by ELISA. All blood cultures were negative. These data suggest that disseminated infection with M. avium-intracellulare is infrequent in Ugandan patients with AIDS; if it occurs at all

"""We are Dying and Getting Finished; Who Will We Leave These Ones For?"" Women's Concerns about Childbearing in Rural Rakai; SW Uganda."

Objectives: To a) Establish the parameters of reproductive choice amongst women who are at high risk for HIV infection. b) Discuss the impact ofthese parameters on issues concerning perinatal transmission. Methods: Research wasdone in amixed ethinicity trading centre in AIDS affected SW Uganda. This ethnographic study used both in-depth; open ended interviews and focus groups with women who believe they are infected or have been tested HIV positive. Results: Regardless of' marriage form' birth control including condom use is perceived to be non negotiable. 'They only use them with those women from out' 'Men want to be associated with many numbers of children... want to leave someone behind' 'Did you come here just to eat?' Women do exercise reproductive choice; either in refusal or without husbands' knowledge (pills; injections; traditional methods). The consquences of refusal to either have sex or produce children are very restrictive; they lead to separation(leaving women economically vulnerable) or the men will go out and find another woman. Little change occurs in relationships where positive sero-status of one or both partners is a real possibility. Evidence suggests that certainty of sero-status gives the impetus to make hard decisions;reproductively. Uncertainty leads to both confusion and fatalism. REgardless of access to cash; sick babies are neglected(immunization; breast feeding; treatment) by both parents. ''This one is slimming anyway''. Mothers experience both the stigma and associated burdens of caring for the sick child. In addition they often decide not to treat themselves. Birth of healthy babies indicate that parents are negative. Conclusion: The voices of women are a testimony to the constraints they expirience sexually and reproductively. They do have a 'choice'. However ;the repercussions of this choice; particularly in high risk environments become restrictive and burdensome

A comparison of different treatment regiments for oral thrush

The objective was to compare the effectiveness of 4 different antifungal regimens in the treatment and maintenance of HIV-associated oral thrush (OT). HIV infected patients with OT were randomised to receive ketoconazole 400 mg/day + glutamic acid 340mg/day to (gp 1); ketoconazole 400mg/day PO (gp 2); Miconazole 2oral gel 2.5ml g