Profil lipidique associé à l'obésité chez les adolescents à Brazzaville, Congo / Lipid profile among obese adolescents in Brazzaville, Congo

Contexte & objectif. Les modifications lipidiques chez les enfants obèses en Afrique noire sont peu documentées. Les objectifs de la présente étude étaient de déterminer chez les adolescents obèses le profil lipidique, et analyser les associations entre quelques paramètres anthropométriques et lipidiques. Méthodes. L'étude transversale a été réalisée à Brazzaville auprès de 82 adolescents âgés de 11 à 18 ans, répartis en 45 sujets obèses, 17 en état de surpoids et 20 poids normal. Des mesures de la taille, du poids, du tour de taille, des plis cutanés sous-scapulaire et tricipital ont été effectuées. Des prélèvements sanguins ont permis de déterminer les concentrations en cholestérol total, cholestérol-LDL, cholestérol-HDL et triglycérides. Résultats. Les concentrations lipidiques notées chez les adolescents obèses étaient significativement supérieures à celles des sujets de poids normal : cholestérol total, 1,70 vs 1,59g/L ; cholestérol-LDL, 1,03 vs 0,88g/L ; triglycérides, 1,18 vs 0,86. Par contre, celles du cholestérol-HDL étaient significativement inférieures : 0,42 vs 0,51g/L. Une corrélation positive a été retrouvée entre le rapport tour de taille/taille et le cholestérol-HDL (r=0,75 ; p=0,031). Conclusion. Nos résultats soulignent la nécessité de renforcer la prise en charge des enfants obèses afin de prévenir les facteurs de risque potentiels des maladies cardiovasculaires à l'âge adulte

Cholesterolemia and triglyceridemia changes in adult with malaria in a hypo-endemic malaria region, Butembo-DR Congo

changes occur commonly among patients affected with malaria. This study aimed to assess lipid changes in blood among patients with malaria in Butembo, a hypoendemic region. Methods: This cross-sectional study, conducted in the Departments of Internal and Parasitology of Matanda Hospital, located in Butembo, from July 1st, 2020, to November 2, 2020; involved 100 patients diagnosed with malaria. Biochemical analyses carried out by three lab technicians were performed among patients who had positive malaria using positive thick film. Plasmodial species, the parasite density, the triglycerides, the total cholesterol, the HDL-cholesterol, the LDL-cholesterol were assessed. Results: Cholesteroleamia and HDLemia demonstrated a low level in 93% and in 61% of participants respectively; whereas 73% of cases showed an increased level of triglycerides in the blood. Lipidemia profile was independently associated with parasite density among patients with malaria. Conclusion: Although the lipid changes in the blood are not specific in the diagnosis of malaria, this study highlighted their status among patients with malaria. Further researches should be conducted to determine their impact on malaria outcomes. Therefore, dyslipidemia could be used in malaria screening.

Sero-molecular Epidemiology of Hepatitis E Virus in Blood Donors, Gezira State, Sudan: A Cross-sectional Study

Background: Hepatitis E virus (HEV) is a hepatotropic pathogen that causes significant morbidity and mortality in humans. It is an important causative agent of viral hepatitis outbreaks. This study investigates the serological and molecular prevalence of HEV in blood donors attending the Central Blood Bank in Wad Medani City in Gezira State, Sudan. Methods: The study adopted a cross-sectional descriptive design. A structured questionnaire was used to collect data concerning demographic information and risk factors associated with HEV transmission. All enrolled participants (N = 300) were screened for HEV IgG antibodies using commercial ELISA kits, then strong positive samples (N = 84) were selected and rescreened for HEV IgM and HEV RNA by RT PCR. SPSS version 24.0 was used for analysis. Results: Out of 300 male participants, 36.3% (109/300) were positive for HEV IgG. However, only one participant was IgM positive, while the HEV RNA was negative. The highest prevalence rates of the virus were 42 (44.6%) among the age group of 31­40 years, 20 (48.8%) in those who consumed food from outside, 13 (50%) in three to four multiple blood donations, and 5 (62.5%) in those who consumed water from the river source. A significant association of HEV IgG prevalence concerning the occupation of the participants being students or farmers was detected using univariate and multivariate analysis (P-value = 0.007).

Blood culture contamination in the departments of paediatrics and child health at two tertiary training hospitals in central South Africa

Background. Bloodstream infections are an important cause of mortality in children. Blood cultures (BCs) remain the primary means of identifying organisms and their antibiotic susceptibility profiles. A shortcoming of BCs is that up to 56% of positive cultures will represent contaminants. Poor adherence to standard practices applicable to BC sampling could explain an unacceptable contamination rate. Objectives. To determine: (i) the BC contamination rate in the departments of paediatrics and child health at two tertiary hospitals in central South Africa; and (ii) BC sampling practices among paediatric clinicians. Methods. The author determined the prevalence of BC contamination by analysis of laboratory data for the period 1 May - 27 August 2019, and assessed possible factors contributing to BC contamination by surveying paediatric medical staff with a self-administered BC practices questionnaire. Results. Of the 244 BCs reviewed, 25.4% were positive. The most commonly isolated pathogens were coagulase-negative staphylococci (CoNS) (33.3%), Escherichia coli (22.2%), Enterococcus faecium (16.7%) and Acinetobacter baumannii (11.1%). In total, 15.2% of the BCs yielded contaminants and 2.9% had polymicrobial growth. The most common contaminant was CoNS. Approximately 68% of clinicians were not aware of BC sampling guidelines, and even among those who were aware of the guidelines, non-compliance was reported. Conclusions. The BC contamination rate was higher than internationally accepted rates. Educating clinicians on specific BC sampling guidelines is strongly recommended to decrease the high rate of contamination observed in this study.

Prevalence of hepatitis B virus infections among blood donors in Federal Capital Territory, Abuja, Nigeria

Background: Transfusion of hepatitis B virus (HBV) infected blood represents a major but avoidable means of HBV transmission, which unfortunately still account for millions of global HBV infections annually. Method: This study determined the prevalence of HBV infection among 550 blood donors aged 18 to 60 years from selected hospitals and blood transfusion centres within the Federal Capital Territory, Nigeria, using hepatitis B surface antigen (HBsAg) rapid diagnostic test (RDT) kit and Enzyme linked Immuno-sorbent Assay (ELISA). Representative positive and negative samples for RDT and ELISA were tested by both conventional and real-time polymerase chain reaction (PCR) assay Results: Forty nine (8.9%) and 14 (2.8%) out of the 550 blood donors tested positive for HBsAg with the RDT and ELISA respectively. Replacement donors had higher prevalence rate of the HBV infection than voluntary donors. The highest prevalence of HBV infection was recorded among the 30­39 year age group. The difference in the rate of infection between the males and the females was not statistically significant (p>0.05). A perfect agreement between RDT and PCR and fair agreement between ELISA and PCR were observed. Conclusion: This study report a high prevalence of hepatitis B virus infections among blood donors in Abuja, Nigeria which underscores the need for proper screening of blood for transfusion to completely eliminate the incidence of transfusion transmitted HBV infections

Utilisation of emergency blood in a cohort of South African emergency centres with no direct access to a blood bank

Introduction: The transfusion of emergency blood is an essential part of haemostatic resuscitation. Locally, where direct access to a blood bank is limited, emergency blood is stored within emergency centres. It was previously suggested that stored blood provides inadequate volumes compared to what is needed. Minimal data are available regarding indications for emergency blood usage. We aimed to describe the utilisation of emergency blood in selected Cape Town emergency centres. Materials and methods :A cross-sectional study was carried out at three secondary level emergency centres (no blood bank), and one tertiary centre (with a blood bank). Data from emergency blood recipients were recorded over a three-month study period. Indications for transfusion, number of units and location of transfusion were recorded. Indications and usage location were described in numbers and proportions. Results : A total of 329 emergency blood units were transfused to 210 patients. Trauma accounted for 39% (n = 81) of cases and other surgical conditions for 22% (n = 47), particularly upper gastrointestinal 11% (n = 24) and perioperative bleeding 8% (n = 16). Medical conditions accounted for 15% (n = 31), with anaemia 13% (n = 27), the most prevalent indication. Gynaecological conditions accounted for 15% (n = 32), mostly ectopic pregnancy 8% (n = 17). The majority of emergency blood, 77% (n = 253) were used in the emergency centres or operating theatres, 6% (n = 21).Conclusion :Trauma remains a major indication for emergency blood transfusion in this setting. This study questions the use of emergency blood for certain non-urgent diagnoses (i.e. anaemia). Given the scarcity of this resource and limitations to access, appropriate use of emergency blood needs to be better defined locally. Ongoing monitoring of the indications for which emergency blood is used, improved transfusion stewardship and better systems to access emergency blood should be a priority in this setting

Determinants of occupational exposure to blood and body fluids, healthcare workers' risk perceptions and standard precautionary practices: a hospital-based study in Addis Ababa, Ethiopia

Abstract Background: The risk of occupational exposure to blood-borne infections is on the rise in hospital settings. The situation is worse in developing countries for a variety of reasons, such as poor working condition, excessive injection use, and poor adherence towards universal precautions. This study was undertaken to assess the determining factors of occupational exposures to blood-borne infections, as well as to describe healthcare workers' risk perceptions and standard precautionary practices in selected hospitals in Addis Ababa, Ethiopia. Methods: A cross-sectional study was conducted from December 2016 to January 2017. A total of 323 healthcare workers from four public hospitals were selected for the study using a simple random-sampling technique. Structured questions administered by an interviewer were used to collect data. Multivariable binary logistic regression was used to identify the determining factors. Results: Healthcare workers' lifetime and one-year prevalence of needlestick injuries were 39.0% (95% CI: 33.6-44.8) and 19.9% (95% CI: 15.2-24.5), respectively. The lifetime and one-year prevalence of blood and body fluid exposures were 42.6% (95% CI: 36.8-48.4) and 29.2% (95% CI: 23.8-34.7), respectively. Almost three out of five healthcare workers, 62.8% (95% CI: 57.0-68.9) had adequate risk perception, and 41.2% (95% CI: 35.4-46.9) adopted good standards of precautionary practice. Service year (AOR: 2.40; 95% CI:1.00-5.77) and having poor standards of precautionary practice (AOR: 2.30; 95% CI: 1.18-4.46) were the determinants of needlestick injuries. Conclusions: The high prevalence of occupational exposure and healthcare workers' sub-optimal practice of taking standard precautions seemed to be common. Long-term and in-service, focused, short-term training were found to be helpful in increasing awareness of the risks and reducing exposure to them

Knowledge of blood donation among adults in north-central Nigeria

Background: About half of the population in Nigeria is medically fit for blood donation but only four in one thousand are voluntary donors. The low level of blood donation has been attributed to poor knowledge, misconceptions, myths, bias, poverty, fear, malnutrition among the population. Therefore, this study assessed the knowledge of blood donation among adults in two selected North Central States of Nigeria.Methods: It was a descriptive cross-sectional study. A total of 3104 respondents comprising of adults between 18 and 60 years were involved in the study. A multistage sampling technique was used and the research tool was interviewer-administered questionnaire. The data generated were entered into the computer and subjected to appropriate statistical analysis using EPI INFO computer software package (version 3.5.3). Pearson Chi Square (χ2) was used to test statistical significance and p-value was set at < 0.05.Results: Majority of the respondents 2565 (82.5%) knew that blood donation save lives. More than three-quarters, 2468 (79.5%), knew where to go for voluntary blood donation. About one-third, (37.1%), demonstrated good knowledge of voluntary blood donation. Older respondents (>60 years) had poor knowledge of blood transfusion compared with younger age groups (p<0.001). Respondents' occupation and educational status were significantly associated with knowledge of blood transfusion (p<0.001)Conclusion: Periodic awareness programme on voluntary blood donation in rural and urban areas across Nigeria is needed. In addition, sensitization of the informal sector on the significance of non-remunerated voluntary blood donation should be given priority

Effect of wooddust inhalation on blood rheology

Occupational exposure to wood dust may bring about some changes in blood indices of humans, especially in developing countries where use of protective gadgets like face masks are not in use. This study is aimed at evaluating changes in blood cell indices, haemostasis and CD 4 count on occupationally exposed workers to wood dust. This randomized study consisted of one hundred (100) male sawmill workers who have been exposed to wood dust by working in these environments without any form of protective masks, for over two years as test subjects and fifty male individuals randomly selected who were not exposed to wood dust as controls. Blood samples were obtained from these workers and analysed for complete blood count using PCE ­ 210N haematology analyser, prothnumbin time test (PTT) and activated partial thromboplastin (APTT) were manually done using commercially purchased kit and CD4 count was performed using the flow cytometry method. Haemoglobin, haemcitrocrit and granutocyte levels increased significantly in test subjects when compared with control subjects (P= 0.037, P=0.026, p=0.0005. Mean lymphocyte levels decreased significantly in test when compared to control subjects (P=0.028). while there were no changes in the other CBC parameters, PT, APTT and CD4 counts in test when compared with control subjects. This suggest that inhalation of wood dust increases haemotocrit, haemoglobin and granulocyte levels, decreased lymphocyte count and a longer exposure time to wood dust significantly affects these parameters. This may imply there is an increased rate of blood flow in the circulation of these individuals

Knowledge and attitude of undergraduates towards blood donation: a cross sectional study of the University of Benin, Benin City

Background: Blood is an essential but scarce therapeutic element. The youth constitute an important age group that can contribute significantly to donor blood availability in health institutions. Their knowledge and attitude towards blood donation may influence their disposition to blood donation practices. Objective: The study seeks to determine the knowledge, attitude and blood donation practices among undergraduate students of the University of Benin. Methodolgy: This is a cross sectional study, conducted at the University of Benin, Benin City. Two hundred pretested questionnaires on knowledge, attitude and practice of blood donation were distributed among consenting undergraduate students across different faculties of the university. Data was analyzed with the statistical package for social science (SPSS IBM) version 20. Result: A total of 155 (79.5%) males and 40 (20.5%) females (M:F of approximately 3.8:1) completed the questionnaires. Their modal age group was 16 ­ 20 years. Sixty eight (34.9%) had good knowledge of blood donation process, 43 (22.1%) had average knowledge and 84 (43.0%) had poor knowledge. Repeat donation rate was 11.3% among the respondent. The practice of blood donation was significantly associated with good knowledge of blood donation process (p = 0.001). Blood donation was higher in those between the age groups of 21 ­ 25 years. Conclusion: Good knowledge of blood transfusion is below average. Blood donation practices is low among undergraduate students of the University of Benin and there is high disposition to family replacement donation

Blood and virus detection on barber clippers

Background. Bleeding from the popular clean-shave 'chiskop' haircut was recently reported as prevalent in South Africa (SA), a country with 6.9 million HIV-infected people.Objectives. To investigate the prevalence of barber hair clipper contamination with blood and HIV and hepatitis B viruses.Methods. Fifty barbers from three townships in Cape Town, SA, were invited to participate. One clipper from each barber was collected immediately after it had been used for a clean-shave haircut. Each clipper was rinsed with phosphate-buffered saline and then submerged in viral medium. The polymerase chain reaction (PCR) was used to identify the blood-specific RNA marker haemoglobin beta (HBB), hepatitis B virus (HBV) and HIV.Results. The clean-shave haircut was the most common haircut requested by clients (78%). Of the clippers collected, 42% were positive for HBB, confirming detection of blood, none were positive for HIV, and 4 (8%) were positive for HBV. Two clippers (clippers 16 and 20) were positive on qualitative HBV PCR. HBV DNA from clipper 16 clustered with genotype A sequences from SA, India, Brazil and Martinique, while clipper 20 clustered with SA genotype D sequences. The clipper 20 sequence was identical to a subtype D sequence (GenBank accession AY233291) from Gauteng, SA.Conclusions. This study confirms that there is significant contamination of barber hair clippers with blood and blood-borne viruses. Hepatitis B was detected with enough DNA copies to pose a risk of transmitting infection. Although HIV was not detected in this small study, the risk of transmission should be quantified. Further studies to investigate barber clipper sterilisation practices and whether the clean-shave hairstyle is an independent risk factor for HIV, HBV and hepatitis C virus infections are warranted. Public education on individual clipper ownership (as is the case with a toothbrush) should be advocated for clean-shave and blade-fade haircuts

Central-line-associated bloodstream infections in a resource-limited South African neonatal intensive care unit

Background. The rate of central-line-associated bloodstream infection (CLABSI) in South African (SA) public sector neonatal intensive care units (NICUs) is unknown. Tygerberg Children's Hospital (TCH), Cape Town, introduced a neonatal CLABSI surveillance and prevention programme in August 2012.Objectives. To describe CLABSI events and identify risk factors for development of CLABSI in a resource-limited NICU.Methods. A retrospective case-control study was conducted using prospectively collected NICU CLABSI events matched to four randomly selected controls, sampled from the NICU registry between 9 August 2012 and 31 July 2014. Clinical data and laboratory records were reviewed to identify possible risk factors, using stepwise forward logistic regression analysis.Results. A total of 706 central lines were inserted in 530 neonates during the study period. Nineteen CLABSI events were identified, with a CLABSI rate of 5.9/1 000 line days. CLABSI patients were of lower gestational age (28 v. 34 weeks; p=0.003), lower median birth weight (1 170 g v. 1 975 g; p=0.014), had longer catheter dwell times (>4 days) (odds ratio (OR) 5.1 (95% confidence interval (CI) 1.0 - 25.4); p=0.04) and were more likely to have had surgery during their NICU stay (OR 3.5 (95% CI 1.26 - 10); p=0.01). Significant risk factors for CLABSI were length of stay >30 days (OR 20.7 (95% CI 2.1 - 203.2); p=0.009) and central-line insertion in the operating theatre (OR 8.1 (95% CI 1.2 - 54.7); p=0.03). Gram-negative pathogens predominated (12/22; 54%), with most isolates (10/12; 83%) exhibiting multidrug resistance. Conclusion. The TCH NICU CLABSI rate is similar to that reported from resource-limited settings, but exceeds that of high-income countries. Prolonged NICU stay and central-line insertion in the operating theatre were important risk factors for CLABSI development. Intensified neonatal staff training regarding CLABSI maintenance bundle elements and hand hygiene are key to reducing CLABSI rates

Attitudes and practices of nursing students confronted with blood exposure accidents in Abidjan

"Background: Blood Exposure Accidents (BEAs) are frequent in healthcare settings and may cause such severe consequences as HIV and Hepatitis B and C infections. Objective: to determine the attitudes and practices of nursing students facing BEAs. Materials and Methods: this was a cross-sectional prospective study conducted from August 16 to 23; 2011 at the ""Institut National de Formation des Agents de la Sante d'Abidjan"" (the National Institute in charge of training Health Workers). Data were collected by means of self-administered questionnaires. Results: out of 266 student nurses included in the study; 73.3% were females while 26.7% were males. Their mean age was 29 years [20 years - 37 years]. A previous training was conducted on BEAs for 67.3% of nursing students. Those students who were immunized against hepatitis were 75.2%. Needle recapping was practiced by 43.6% of nursing students. Unclean needles were eliminated in containers by 96.2% of the Background: Blood Exposure Accidents (BEAs) are frequent in healthcare settings and may cause such severe consequences as HIV and Hepatitis B and C infections. Objective: to determine the attitudes and practices of nursing students facing BEAs. Materials and Methods: this was a cross-sectional prospective study conducted from August 16 to 23; 2011 at the ""Institut National de Formation des Agents de la Sante d'Abidjan"" (the National Institute in charge of training Health Workers). Data were collected by means of self-administered questionnaires. Results: out of 266 student nurses included in the study; 73.3% were females while 26.7% were males. Their mean age was 29 years [20 years -37 years]. A previous training was conducted on BEAs for 67.3% of nursing students. Those students who were immunized against hepatitis B were 75.2%. Needle recapping was practiced by 43.6% of nursing students. Unclean needles were eliminated in containers by 96.2% of thestudents and waste containers were within close reach of only 65.4%. Glove wearing was systematic in 77.1% of the students. Before the survey 38% of nursing students had been victim of BEAs at least once. Those BEAs were not reported in 68.3% of the victims.Conclusion: the attitudes and practices of nursing students are inadequate with regards to BEAs. A module on Hospital Hygiene is necessary in view of improving the training of nursing students."

Les accidents d'exposition au sang dans les maternités de Bangui

Introduction : Les accidents d'exposition au sang constituent une hantise pour les agents de santé travaillant en contact du sang et de ses dérivés. Leur prise en charge constitue un défi pour la réduction de l'infection à VIH parmi le personnel de santé. L'objectif de notre étude est de déterminer la prévalence des accidents d'exposition au sang dans les maternités de Bangui, d'identifier les circonstances de survenue, les attitudes et les pratiques des agents de santé après ces accidents. Patients et méthodes : Nous avons mené une étude transversale à visée descriptive et analytique allant du 1er novembre au 31 décembre 2013. La population d'étude était représentée par le personnel de santé et techniciens de surface exerçant dans toutes les maternités publiques de Bangui. Résultats : Nous avions interrogé 260 personnes. La prévalence des accidents d'exposition au sang était de 60%. Les victimes étaient majoritairement des femmes (71,2%) avec un âge moyen de 37 ans. La plupart du personnel (91,2%) n'était pas immunisée contre l'hépatite B et 58,5% ont déclaré avoir été sensibilisés sur les accidents d'exposition au sang. Les accidents par projection de liquide biologique (63,5%) étaient les plus représentés suivis de piqures par une aiguille (53,2%). La principale réaction des victimes après l'accident était le lavage de la lésion (87,8%), suivi d'une application d'antiseptique (35,2%). Conclusion : Les accidents d'exposition au sang par leur ampleur demeurent encore un problème de santé publique dans nos milieux de soins. L'insuffisance en matériels de protection, la sous- déclaration des cas et la faible couverture vaccinale contre l'hépatite B du personnel de santé sont autant de facteurs de risque. La prise en compte des problèmes identifiés contribuerait à la réduction de la propagation de l'infection à VIH et des hépatites dans nos milieux de soins

Blood Bacterial Isolates in Sickle Cell Anaemia

Background:Sickle cell anaemia is a haemoglobinopathy characterized by the presence of sickle haemoglobin. Sickling can occur in these patients with sluggish flow of blood which accentuates the sickling phenomenon and susceptibility to infection. Notable among such infections are those caused by bacteria such as Streptococcus pneumoniae; Salmonella; Staphylococcus and Haemophilus influenzae. Aims: To ascertain the incidence of bacteria isolates among sickle cell individuals and to determine the antibiotics sensitivity pattern of such organism isolated.Methods: Thirty five (35) blood samples were randomly collected from sickle cell anaemia patients attending the University of Benin Teaching Hospital and Central Hospital; Benin City. Fifteen (15) blood samples comprising seven (7) with Hb-genotype AA and eight (8) Hb-genotype AS served as controls. Verbal informed consent was gotten from them. Cultural method was used in isolating microorganisms present in the blood samples.Results: There was strong association between genotype and bacterial isolates with genotype SS being more infected. A significant weak association exists between gender and bacterial isolate among sicklers. Age; tribe and occupation did not have any association with bacterial isolate among the studied population. Staphylococcus aureus was the predominant isolate (66.7); while ciprofloxacin and perfloxacin were the most active drugs against the isolates.Conclusion: From our study; 25.7of sickle cell anaemia patients had bacterial infection with a higher rate in females and Staphylococcus aureus being the most incriminated organism

Accidents d'exposition au sang chez les professionnels de sante a l'Hopital Biamba Marie Mutombo

Contexte : Les accidents d'exposition au sang (AES) constituent un des risques les plus importants auxquels font face les professionnels de sante. Lors d'un AES; bien que de nombreux pathogenes puissent etre transmis; les virus induisant un portage chronique en cas de contamination dominent le risque; et justifient a eux seuls; les mesures de prevention et de prophylaxie post-exposition. Il s'agit du VIH; des Virus des hepatites B et C. Cependant; l'ampleur reelle du probleme n'est pas connue dans notre pays; la Republique Democratique du Congo (RDC). Objectif : Evaluer la frequence des AES chez les professionnels de sante de l'Hopital Biamba Marie Mutombo; en decrire les caracteristiques et determiner les categories professionnelles les plus concernees. Methode : Une enquete transversale a ete menee au mois d'Aout 2009 et reprenant les AES survenus au cours des 12 derniers mois a l'HOPITAL BIAMBA MARIE MUTOMBO de Kinshasa. Une fiche d'enquete a ete utilisee; sollicitant les informations generales sur le professionnel ainsi que les accidents de blessures et la projection du sang ou d'un autre liquide biologique survenus a l'hopital au cours de l'annee derniere. Resultats : Parmi les 219 professionnels enquetes; seuls 24des participants etaient informes sur les risques encourus par l'exposition aux pathogenes sanguins. 40ont declare avoir eu au moins une blessure accidentelle et 16une eclaboussure d'un liquide biologique au cours de l'annee derniere. Les Infirmiers ont reporte le plus grand nombre d'accidents (piqures et projections de liquides biologiques). Les AES ont ete plus dus aux aiguilles avant l`acte professionnel. Conclusion : Pres de 50des AES pouvaient etre evites par des mesures simples; malheureusement pas toujours connues des professionnels de sante

Certain Red Blood Cell Indices of Maternal and Umbilical Cord Blood in Owerri; Nigeria: A Preliminary Report

BACKGROUND: Umbilical cord blood analysis may give a clue to the state of health of both pregnant mothers and their neonates. However, there is paucity of literature on some of these indices from our area.OBJECTIVES:This present study determined the red blood indices of maternal and umbilical cord blood in Owerri, Nigeria.METHODS:Pregnant mothers aged 18 - 42 years who booked and received antenatal care until vaginal delivery at the antenatal clinics of two tertiary health care centres in Owerri, Nigeria were divided into five age groups I - V. Maternal blood samples were obtained immediately after delivery of the baby. The umbilical blood samples were collected from the umbilical cord of the baby at the end of the second stage of labour. The haemoglobin (Hb) concentration and packed cell volume (PCV) were determined using standard procedures. The mean corpuscular haemoglobin concentration (MCHC) was calculated mathematically.RESULTS:The result of the cord blood haemoglobin concentration and packed cell volume were significantly higher than the maternal values (14.22 ± 1.25 g/dl versus 11.20 ± 0.92g/d and 42.6 9± 3.80% versus 33.67 ± 2.71% respectively; (P < 0.0001).However, there was no significant differences between cord blood and maternal mean corpuscular haemoglobin concentration (33.24 ±0.23% versus 33.29 ± 0.45 % ;P = 0.310). Furthermore, a positive linear Pearson's correlation was observed between the mean Hb and PCV of cord blood and maternal blood (r=1.11 and r=1.15 respectively <0.0001).CONCLUSION:This result provides a baseline data for further studies on establishing a reference value for maternal and umbilical cord packed cell volume and haemoglobin concentration in our locality