ABSTRACT
Des analyses chimiques qualitatives et quantitatives ont ete effectuees sur trois medicaments antidiarrheiques utilisees en medecine traditionnelle dans la province du Centre (Cameroun): myrianthus arboreus (medication I); combretum sp (medication II); holarrhena sp (medication)
Subject(s)
Antidiarrheals , Chemistry , Diarrhea/drug therapy , Medicine , PlantsABSTRACT
L'accessibilite des enfants de moins de 5 ans a la therapie de rehydratation orale (TRO) au Congo semble contraster avec la prescription et la consommation massives d'antidiarrheiques. Une etude realisee a Brazzaville ou les maladies diarrheiques constituent la deuxieeme cause de morbidite infantile; a revele que le cout direct de traitement d'un episode diarrheique represente 14;8 pour cent du revenu du Congolais moyen; la pharmacie d'approvisionnement; organe etatique; consacre 15;35 pour cent de son budget a l'achat des antidiarrheiques; les ordonnances d'antidiarrheiques sont prescrites aux enfants dans 88 pour cent des cas
Subject(s)
Antidiarrheals , Diarrhea/drug therapy , Diarrhea/economics , Health Education , Health Expenditures , Rehydration SolutionsABSTRACT
A study to determine the in vitro activity of antibiotics to bacterial pathogens isolated from diarrhoea stools of 125 patients reporting to the Paediatric Filter Clinic at Malindi District Hospital with acute diarrhoea was done. The ages of the patients ranged from one to five years. Samples of diarrhoea stools were collected before drug administration. 33 strains of Enterobacteriacea comprising 12 strains of pathogenic Escherichia coli; 13 strains of Salmonella SPP and 8 strains of Shigella SPP were isolated and minimum inhibitory concentration of five antibiotics determined. 5 pure antibiotic powders; namely; ampicillin; tetracycline; kanamycin; trimethoprim-sulfamethoxazole and nalidixic acid were tested using the agar dilution method (Muellerinton agar). The minimum inhibitory concentration (MIC) of the 5 antibiotics used ranged between 8#gml-1 and 128#gml-1 excep for t trimethoprin-sulfamethoxazole which had a MIC range of 0.25#gml-1 to 16#gml-1. Hyper resistance of the isolates was observed for ampicillin; tetracycline; kanamycin and nalidixic acid. The results of this work suggest that there is circulation of resistant strains of bacteria causing diarrhoea within the community around Malindi
Subject(s)
Anti-Bacterial Agents , Diarrhea , Diarrhea/drug therapy , Drug Evaluation , InfantABSTRACT
A study was carried out in four rural areas of Zimbabwe to assess the acceptabilty; feasibility and accuracy of sugar - salt solutions and to investigate the action taken during a recalled episode of diarrhoea in a child. Only 5 per cent of respondents gave the child a sugar-salt solution at home during the described illness yet a majority (52 per cent) claimed knowledge of oral rehydration techniques