Nonspecific Colitis a Forgotten Entity in Central Sudan

Background: Nonspecific colitis is an inflammatory Bowel Disease (IBD) that runs a clinically benign course. Histopathologically it is characterized by superficial mucosal erosions with lymphocytic infiltration in the lamina propria with no granuloma. Aim of this study: is to describe the clinical presentation of Non-Specific Colitis (NSC); and to evaluate its response to 5-aminosalicylic acid (5-ASA) in Sudanese patients. Setting and Design: This study is a prospective cohort. A total of 26 patients presenting with bloody; mucoid diarrhoea; lower abdominal pain or colonic mass were included in the study. Methods and Materials: A total of 26 patients presenting with bloody mucoid diarrhoea; lower abdominal pain with or without colonic mass were included in the study. All patients underwent colonoscopy. Statistical analysis: A descriptive statistical analysis was done using SPSS. Results: 19 () of patients were males and 7 were females with male to female ratio of 3:1. The majority of patients 16 (61.6) had bloody diarrhea while 18 (69.2) opened their bowel 4-6 times a day. The majority 10 (38.8) had rectum and sigmoid involvement. All patients showed a good response to 5-ASA. Conclusions: This study showed that NSC has clinical features that are very much similar to mild UC with a rather good clinical response to oral 5-ASA

Childhood Inflammatory Bowel Disease in Libya: Epidemiological and Clinical Features

Background et Aims: Inflammatory bowel disease is thought to be rare in Libya. The aim is to determine the prevalence of juvenile onset inflammatory bowel disease in Libya. Setting: Al-Fateh childrens' hospital; Benghazi; Libya. Methods: This is a retrospective study of all cases diagnosed over 10 years (1997-2006) with either ulcerative colitis; Crohn's disease or indeterminate colitis. Inclusion criteria were age 15 years at time of presentation who were resident in the eastern part of the country and who diagnosed with inflammatory bowel disease. Clinical features were outlined using a proforma. Results: Sixteen cases were diagnosed with inflammatory bowel disease; of whom 11 were males (M:F ratio of 1.5:1). The prevalence and incidence rates in the year 2006 were 3.6 and 0.9 per 100;000 children; respectively. The incidence rate increased from 0.2 in 2002 to 0.9 in 2006 (Z score of 39.87; p); abdominal pain; anorexia and weight loss in 9 (56.2); anemia in 7 (43.75) and vomiting in 6 (37). Ileopancolitis was found in 3 patients whereas 6 patients had ileocecal disease. Conclusions: Childhood inflammatory bowel disease in this population is not so rare and it is increasing. The clinical pattern is similar to that reported by others