Attitude and knowledge of women between 45 and 65 years on menopause syndrome at the university college hospital, Ibadan, Nigeria

This research was designed to find out the attitude and knowledge of women between 45 and 65 years on menopause syndrome and its management. The study was conducted in University College Hospital located in Ibadan North Local Government of Oyo state. A self-designed forced-choice questionnaire was distributed to 100 women using random sampling technique. Furthermore, our study showed that most women view the onset of menopause positively and that few seek treatment. They report relatively low prevalence of menopausal symptoms, with the most significant being irregular menstrual cycles and increased blood pressure and urinary tract infections. Furthermore, our study revealed that 41% of the participants had no idea why their menstrual period stopped, while why 60% of the women had no idea what could be done to reduce menopausal symptoms. This study reveals a low level of awareness about menopausal syndrome and more should be done. (Afr J Reprod Health 2022; 26[5]: 57-62).

Profile of the female athlete triad among elite Kenyan endurance athletes and non-athletes

Women participating in endurance sports are at risk of presenting with low energy availability (EA), menstrual dysfunction (MD), and low bone mineral density (BMD), collectively termed the female athlete triad (FAT or TRIAD). Therefore, the purpose of the study was to determine the profile of the TRIAD among elite Kenyan female athletes and among non-athletes. There were 39 participants (athletes: 25, non-athletes:14) who provided the data for this study. Exercise energy expenditure (EEE) was deducted from energy intake (EI), and the remnant energy normalized to fat free mass (FFM) to determine energy availability (EA). Weight of all food and liquid consumed during three consecutive days determined EI. EEE was determined after isolating and deducting energy expended in exercise or physical activity above lifestyle from the total energy expenditure output as measured by Actigraph GT3X+. Dual energy x-ray absorptiometry (DXA) determined both FFM and BMD. Menstrual function was determined from a daily temperature-menstrual log kept by each participant for nine continuous months. Low EA (<45 kcal/kgFFM.d-1) was evident in 61.53% of the participants (athletes: 28.07 ±11.45 kcal/kgFFM.d-1, non-athletes: 56.97 ±21.38 kcal/kgFFM.d-1). The overall 36% MD seen among all participants was distributed as 40% among the athletes, and 29% among non-athletes. None of the athletes was amenorrheic. Low BMD was seen in 79% of the participants (athletes: 76%, non-athletes:86%). Overall, 10% of the participants (athletes: 4, non-athletes: 0) showed simultaneous presence of all three components of the TRIAD. The Independent sample t-test showed significant difference (t=5.860; p< 0.001) in prevalence of the TRIAD between athletes and non-athletes. The hypothesized higher prevalence of the TRIAD among athletes compared to non-athletes was partially accepted. To alleviate conditions arising from low EA, both athletes and their coaches need regular education on how to ensure they adequately meet specific dietary and nutritional requirements for their competition events

Association between energy availability and menstrual function in elite Kenyan runners

Low energy availability (EA) has been recognized as an instigator of menstrual dysfunction and subsequent hypoestrogenism that leads to deterioration in bone health. Elite Kenyan male athletes have been reported to often function under low energy balance. Therefore, the purpose of this study was to determine EA and menstrual function (MF) among elite Kenyan female athletes; and to explore the association between EA and MF in the athletes. The data were collected from 25 elite Kenyan runners and 14 non-athletes. Energy intake (EI) minus exercise energy expenditure (EEE) normalized to fat free mass (FFM) determined EA. EI was determined through weight of all food and liquid consumed over three consecutive days. EEE was determined after isolating and deducting energy expended in exercise or physical activity above lifestyle level from the total energy expenditure output as measured by Actigraph GT3X+. FFM was assessed using DXA. A daily temperature-menstrual log kept for nine continuous months was used to establish menstrual function. Overall, EA below 45 kcal/kgFFM.d-1 was seen in 61.53% of the participants (athletes: 28.07 ±11.45 kcal/kgFFM.d-1, non-athletes:56.97 ±21.38 kcal/kgFFM.d-1). Results on menstrual dysfunction were as follows: oligomenorrhea (athletes: 40%; non-athletes: 14.3%) and amenorrhea (non-athletes: 14.3%). None of the athletes were amenorrheic. Results did not show any significant association between EA and MF, but the low to sub-optimal EA among elite Kenyan female athletes raises concern for their future menstrual and bone health. . Educating the athletes and coaches will enhance achievement of the specific dietary and nutritional needs appropriate to their competition events

The Effect of Mefenamic Acid and Naproxen on Heavy Menstrual Bleeding: A Placebo-Controlled Study

Background. Heavy menstrual bleeding is a common complaint. Various therapeutic approaches have been suggested.Aim. To compare the efficacy of mefenamic acid and naproxen in reducing heavy menstrual bleeding.Methods. Women referred to an outpatient centre for treatment of heavy menstrual bleeding were recruited. Participants who met the inclusion criteria were evaluated for 6 menstrual cycles. During 3 control cycles they recorded the amount of their bleeding on the Pictorial Blood Assessment Chart to confirm that their menstrual bleeding was heavy. One hundred and twenty participants were then randomly assigned to receive mefenamic acid; naproxen or placebo; and asked to fill in the same questionnaires during 3 intervention cycles. The data were analysed using SPSS version 15 for Windows.Results. Participants receiving mefenamic acid experienced a marked decrease in bleeding during the 3 months of intervention; an initial sharp decrease being followed by a further lesser decrease (p0.05 within group). Bleeding lessened dramatically in the first month of the intervention in participants receiving naproxen; and dropped still further in the second and third months (p0.05 within group). In the placebo group there were slight changes in bleeding during the intervention (p0.05 within group). However; the total decrease in bleeding was greatest in the naproxen arm; and the differences between the groups were statistically significant (p0.05 between groups).Conclusion. All three interventions had positive effects on the mean amount of bleeding; although naproxen was more effective than mefenamic acid and much more effective than placebo

Changes in Total and Differential white Cell Counts; Total Lymphocyte and CD4 Cell Counts during the Menstrual Cycle in Healthy Female Undergraduate Students in Port Harcourt; Nigeria

Background: Published reports on the possible changes in the various immune cell populations; especially the total lymphocyte and CD4 cell counts; during the menstrual cycle in Nigerian female subjects are relatively scarce. Aim: To determine possible changes in the total and differential white blood cell [WBC] counts; total lymphocyte count [TLC] and CD4 cell count during the menstrual cycle in apparently healthy reproductive aged female undergraduate students in Port Harcourt; Nigeria. Methods: A total of 61 apparently healthy HIV sero-negative female undergraduate students of the University of Port Harcourt; Nigeria aged between 17 and 30 years; were recruited into the study. Subjects were allowed their normal daily routines but restricted from excessive physical activities for the duration of the study. After a menstrual history; blood was collected from each subject at the different phases of the menstrual cycle: menstrual; follicular; ovulatory and luteal. Total WBC and differential counts were determined manually; TLC was obtained by multiplying the percentage lymphocytes by the total WBC count; CD4 cell counts were determined by flow cytometry. Results: Single factor analysis of variance showed significant differences only in the values of total WBC; and differential neutrophils; lymphocytes; and eosinophil counts [p0.05]; no significant differences were observed in the values of monocytes; basophils; TLC and CD4 cell count during the phases of the menstrual cycle.Conclusion: The present study confirms previous reports of significant physiological variations in the leukocyte counts during the phases of the normal menstrual cycle. However; our results suggest that apparently TLC and CD4 cell count do not undergo a similar physiological variation

Age at menarche and the menstrual pattern of Igbo Women of South-east Nigeria

This study determines the age at menarche and menstrual pattern of an Igbo population in 12 randomly selected rural communities of Ebonyi State. Information on recalled ages at menarche, menstrual flow duration and cycle length was collected using a semi structured questionnaire over three months. 1209 women of reproductive age were interviewed. The mean age at menarche was 15.0 years and this declined over the years. The mean menstrual flow duration and cycle lengths were 3.3 days and 29.7 days respectively. Only 10.2% had a menstrual cycle length of 28 days. Account should be taken of the average length of 29-30 days in the rural Igbo population when calculating the expected date of delivery and in the family planning clinics. (Afr Reprod Health 2008; 12[1]:90-95)

Etude epidemio-clinique de la menarche en milieu scolaire (2eme cycle fondamental et lycees) a Bamako de Mars a Avril

Nous avons realise une etude transversale de mars a avril 2004 aupres de 1300 eleves et lyceennes du district de Bamako. Il en ressort que : L'age de la menarche est de 13;22 ans. Les facteurs susceptibles d'influencer la date d'apparition des 1eres regles sont : le niveau socio-economique des parents; le niveau de reussite scolaire des filles. Les filles dont les parents sont d'un niveau socio-economique eleve sont beaucoup plus precoces et les filles en retard scolaire presentent un retard dans la date d'apparition des 1eres regles. 63;3 p.100 des scolaires avaient des connaissances sur le phenomene des regles avant leur survenue et la premiere source de renseignement etait fournie par la mere a 39;9 p.100 L'age au premier rapport sexuel est de 15;74 ans. Le partenaire sexuel des scolaires n'a pas utilise le preservatif dans 66;7 p.100 des cas. La peur des infections sexuellement transmissibles represente la cause majeure de l'utilisation du preservatif

Comparison of estimates of gestational age using last menstrual date; biparietal diameter; and ballard score

The gestational age of 30 Ghanaian neonates was estimated prenatally from ultrasound measurements of biparietal diameter (BPD); postnatally from the neonate's neurological and physical criteria using Ballard score. These two estimates were compared with the gestational age using the date of the last menstrual period (LMP) in mothers. The means (+/-SD) for the estimated gestational age were 38.96 +/- 2.77 weeks; 38.83 +/- 2.74; and 39.30 +/-2.03 for LMP;BPD; and Ballard score respectively. The difference between BPD and Ballard score was statistically significant (t=2.16;P0.05). While the three methods appear to be concordant among neonates 37 weeks and older; the estimates using Ballard score over-estimated the gestational age of neonates below 37 weeks