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1.
Article in English | AIM | ID: biblio-1417210

ABSTRACT

Introduction: L'objectif général de notre travail était d'apporter une description épidémiologique et clinicopathologique du cancer de l'endomètre au Gabon. Patients et méthode: Cette étude descriptive et rétrospective a été réalisée à l'Institut de Cancérologie de Libreville chez les patientes atteintes du cancer de l'endomètre sur une période de 7 années (de janvier 2012 à octobre 2018). Résultats: Cette étude a inclus 32 patientes et les résultats obtenus ontmontré que ce cancer au Gabon est plus fréquent chez la femme multipare, que histologiquement le type 1 est le plus souvent rencontré et que ce cancer est de haut grade de malignité. De ce travail ressort également la difficulté du suivi des patientes. Conclusion: Le cancer de l'endomètre étant un cancer souvent d'emblée de mauvais pronostic, il est d'intérêt de mettre en place une stratégie de prévention et de management adapté.Mots clés: cancer, endomètre, étude clinicopathologique, suivi, Gabon Abstract:Introduction:The general objective of our work was to provide an epidemiological and clinicopathological description of endometrial cancer in Gabon.


Introduction: The general objective of our work was to provide an epidemiological and clinicopathological description of endometrial cancer in Gabon. Epidemiological and clinicopathological profile of... Patients and method: This descriptive and retrospective study was carried out at Cancer Institute of Libreville in patients with endometrial cancer over a period of 7 years (from January 2012 to October 2018) . Results: This study included 32 patients and the results obtained showed that this cancer in Gabon is more frequent in multiparous women, that histologically type 1 is most often encountered and that this cancer is of high grade malignancy. This work also shows the difficulty of following up patients. Conclusion: As endometrial cancer is often a cancer with a poor prognosis , it is interest to put in place an appropriate prevention and management strategy.


Subject(s)
Humans , Female , Methods , Prognosis , Pathological Conditions, Signs and Symptoms , Therapeutics , Endometrial Neoplasms , Aftercare , Disease Management , Endometrium , Hysterectomy, Vaginal
2.
Article in French | AIM | ID: biblio-1362757

ABSTRACT

Introduction : les pathologies ORL de l'enfant sont multiples et diversifiées. Le cout élevé de leur prise en charge ainsi que l'accessibilité limitée aux soins démontrent la nécessité de renforcer la prévention. Le but de travail était de recenser les aspects épidémio-cliniques des affections ORL de l'enfant et d'en analyser les mesures de prévention primaire. Méthode : l'étude s'est déroulée dans le service d'ORL-CCF du CNHU de Cotonou. Elle a été descriptive avec un recrutement prospectif du 1er Janvier au 30 Juin 2018. Ont été inclus les enfants de 0 à 18 ans reçus en consultation ORL. Les données cliniques ont été analysées. Résultats : les enfants ont représenté 25,79 % des consultants (311 enfants sur 1206 patients). L'âge moyen était de 7,20 ± 5,36 ans et 164 parmi eux (52,73 %) étaient de sexe masculin. Les pathologies observées étaient : infectieuses/inflammatoires 181 cas (58,20 %), traumatiques 56 cas (18 %), fonctionnelles 26 cas (8,36 %), tumorales 20 cas (6,43 %), malformatives 17 cas (5,47 %) et vasculaires 11 cas (3,54 %). Les dix principales pathologies ORL infantiles étaient : otites moyennes aiguës 60 cas (19,29 %), corps étrangers ORL 47 cas (15,11 %), hypertrophies amygdaliennes 36 cas (11,58 %), rhinopharyngites 21 cas (06,75 %), amygdalites 19 cas (6,11 %), hypoacousies isolées 18 cas (5,79 %), rhinites 17 cas (5,47 %), freins de langue 9 cas (2,89 %), adénopathies cervicales 7 cas (2,25 %) et otite externe 5 cas (1,61 %). Conclusion : Les pathologies ORL de l'enfant sont fréquentes en consultation. Elles sont dominées par les infections et les traumatismes. Le suivi rigoureux du calendrier vaccinal et les sensibilisations sur les règles d'hygiène de vie des enfants pourraient contribuer à la réduction de leurs incidences


ENT pathologies in children are multiple and diverse. The high cost of their care and the limited accessibility to care demonstrate the need to strengthen prevention. The aim of the work was to identify the epidemiological and clinical aspects of ENT disorders in children and to analyze their primary prevention measures. Method: The study was conducted in the Department of Ear-Nose-Throat Head and Neck Surgery (ENT HNS-CFS) of the National University Hospital Center of Cotonou. It was a descriptive study realized through a prospective enrollment. We included in this study, children aged from 0 to 18 years that were received in the ENT's consultation during the period from January 1st to June 30th, 2018. Socio-demographic and clinical data were analyzed. Results: Children represented 25.79% of the consultants (311 children among 1206 patients). The mean age was 7.20 ± 5.36 years and 164 among them (52.73%) were male. The pathologies identified were: the infectious / inflammatory pathologies with 181 cases (58.20%), the traumatic ones with 56 cases (18%), functional with 26 cases (8.36%), tumoral with 20 cases (6,43%), malformations with 17 cases (5.47%), and vascular pathologies with 11 cases (3.54%). The ten most common childhood ENT diseases were: acute otitis media with 60 cases (19.29%), ENT foreign bodies with 47 cases (15.11%), tonsil hypertrophies with 36 cases (11.58%), Rhinopharyngitis with 21 cases (06.75%), tonsillitis with 19 cases (6.11%), isolated hearing loss with 18 cases (5.79%), rhinitis with 17 cases (5.47%), tongue brakes with 9 cases (2.89%), cervical lymphadenopathies with 7 cases (2.25%) and external otitis with 5 cases (1.61%). Conclusion: The ENT pathologies of the child are frequent in consultation. They are dominated by infections and trauma. Rigorous monitoring of the immunization schedule and raising awareness of healthy lifestyle rules for children could help reduce their impacT


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Otorhinolaryngologic Diseases , Pathological Conditions, Signs and Symptoms , Disease Management , Disease Prevention
3.
Ibom Medical Journal ; 14(4): 427-431, 2021.
Article in English | AIM | ID: biblio-1353275

ABSTRACT

Background: In December 2019, an atypical form of pneumonia was discovered in Wuhan, China and it has spread to different parts of the world including Nigeria. Testing for the causative agent which is the severe acute respiratory distress syndrome coronavirus-2 is one of the strategies to contain the pandemic. For some reason, some patients with clinical symptoms suggestive of COVID-19 may refuse to be tested for the disease. Methodology: A review of studies conducted on COVID-19 testing and ethical dilemma associated with it was done using Google Scholar, PubMed and Cochrane reviews. Conclusion: Ethical dilemma exists in testing for COVID-19 as some patients may refuse testing even when it is necessary and they present with symptoms suggestive of COVID-19. The right to autonomy according to the principles of medical ethics is necessary for every medical consultation but may not be important in pandemics as the person becomes a health threat and harmful to the public.


Subject(s)
Pathological Conditions, Signs and Symptoms , Ethics, Medical , COVID-19 , Psychology , Personal Autonomy
4.
Ghana Med. J. (Online) ; 54(4): 52-61, 2020. ilus
Article in English | AIM | ID: biblio-1262313

ABSTRACT

Introduction: Since the declaration of COVID-19 by the World Health Organisation (WHO) as a global pandemic on 11th March 2020, the number of deaths continue to increase worldwide. Reports on its pathologic manifestations have been published with very few from the Sub-Saharan African region. This article reports autopsies on COVID19 patients from the Ga-East and the 37 Military Hospitals to provide pathological evidence for better understanding of COVID-19 in Ghana. Methods: Under conditions required for carrying out autopsies on bodies infected with category three infectious agents, with few modifications, complete autopsies were performed on twenty patients with ante-mortem and/or postmortem RT -PCR confirmed positive COVID 19 results, between April and June ,2020. Results: There were equal proportion of males and females. Thirteen (65%) of the patients were 55years or older with the same percentage (65%) having Type II diabetes and/or hypertension. The most significant pathological feature found at autopsy was diffuse alveolar damage. Seventy per cent (14/20) had associated thromboemboli in the lungs, kidneys and the heart. Forty per cent (6/15) of the patients that had negative results for COVID-19 by the nasopharyngeal swab test before death had positive results during postmortem using bronchopulmonary specimen. At autopsy all patients were identified to have pre-existing medical conditions. Conclusion: Diffuse alveolar damage was a key pathological feature of deaths caused by COVID-19 in all cases studied with hypertension and diabetes mellitus being major risk factors. Individuals without co-morbidities were less likely to die or suffer severe disease from SARS-CoV-2


Subject(s)
COVID-19 , Autopsy , Ghana , Hospitals, Military , Pathological Conditions, Signs and Symptoms
5.
S. Afr. fam. pract. (2004, Online) ; 61(1): 21-26, 2019. ilus
Article in English | AIM | ID: biblio-1270078

ABSTRACT

The introduction of antiretroviral medication has changed the epidemiology, morbidity and mortality of HIV disease. Nevertheless,cutaneous disorders due to HIV infection remain a major problem in HIV-infected patients. These disorders are mainly infections,inflammatory and neoplastic in origin. Some of these disorders occur at normal CD4 cell counts, while others occur typically at low CD4 cell counts. Clinicians should be aware of various presentations of these disorders and their treatment as they can impact negatively on patient's quality of life


Subject(s)
Dermatologic Agents , HIV Serosorting , Pathological Conditions, Signs and Symptoms
6.
Article in French | AIM | ID: biblio-1271838

ABSTRACT

L'objectif était d'étudier la connaissance des signes de danger de la mère et du nouveau-né ainsi que les facteurs associés parmi les femmes du district sanitaire de Sig-Noghin. Il s'est agi d'une étude transversale analytique menée du 1er avril au 30 mai 2016. Elle a concerné un échantillon de 429 femmes. L'entretien a été la technique d'enquête utilisée. Pour l'identification des facteurs associés, une régression logistique fut réalisée. Parmi les participantes 16,5 % ; 11,1 % et 6,3 % ont pu citer au moins trois (3) signes de danger respectivement de la grossesse, du postpartum et du nouveau-né. L'âge de la femme (OR aj 6,14 [1,06-35,61]), le niveau d'instruction (OR aj 3,19 [1,59-6,38]), le nombre de grossesses (OR aj 3,30 [1,13-9,62]) et le nombre de consultations prénatales (OR aj 1,77 [1,09-3,46]) étaient les facteurs statistiquement associés à la connaissance des signes de danger de la mère. Aucun des facteurs étudiés n'était associé à la connaissance des signes de danger du nouveau-né. En somme, le niveau de connaissance des signes de danger de la mère et du nouveau-né reste faible. Il est impératif de promouvoir davantage la sensibilisation des femmes enceintes et accouchées tout en impliquant la communauté dans laquelle celles-ci vivent


Subject(s)
Burkina Faso , Infant, Newborn , Pathological Conditions, Signs and Symptoms , Postpartum Period , Pregnancy, High-Risk
7.
Med. Afr. noire (En ligne) ; 64(02): 85-89, 2017. ilus
Article in French | AIM | ID: biblio-1266226

ABSTRACT

La dengue est une maladie émergente dont l'incidence et la sévérité sont en augmentation dans le monde. La forme classique est bénigne mais elle peut évoluer vers la forme hémorragique qui peut être fatale. Nous rapportons un cas de dengue hémorragique avec comme objectif de décrire les caractéristiques cliniques et les difficultés de son diagnostic dans notre contexte. Les similitudes des manifestations cliniques de la dengue avec les autres maladies infectieuses, rendent obligatoire la mise à disposition des moyens de diagnostic fiables au laboratoire. En l'absence de vaccin, les mesures de prévention doivent être respectées. Une prise en charge médicale appropriée permet de réduire considérablement la létalité


Subject(s)
Burkina Faso , Case Reports , Disease Management , Pathological Conditions, Signs and Symptoms , Severe Dengue/diagnosis
8.
Med. Afr. noire (En ligne) ; 64(07): 359-362, 2017.
Article in French | AIM | ID: biblio-1266261

ABSTRACT

Introduction : Le Prune Belly Syndrome (PBS) (ou syndrome d'Eagle-Barrett) est une affection congénitale rare qui touche principalement les garçons. Il est caractérisé par la triade classique aplasie musculaire de la paroi abdominale antérieure, cryptorchidie bilatérale ou agénésie des testicules chez le garçon et malformation des voies urinaires.Observation : Il s'agissait d'un garçon de deux mois admis pour investigation d'une anomalie de la paroi abdominale antérieure constatée depuis la naissance. L'examen physique avait permis de retrouver une aplasie de la musculature abdominale avec un abdomen distendu flasque et étalé, une peau fripée faisant apparaitre l'empreinte des anses intestinales. Au niveau génital il y avait un hypospadias balano-prépucial avec un prépuce en chapeau de gendarme, une cryptorchidie bilatérale. L'échographie abdomino-pelvienne avait montré une mégavessie, une urétéro-hydronéphrose bilatérale et une absence de visibilité des testicules. L'urétro-cystographie rétrograde était normale. Le reste du bilan malformatif était normal.Conclusion : Le PBS reste une affection congénitale rare. Les formes avec absence de manifestations extra-urinaires sont de bon pronostic


Subject(s)
Cryptorchidism , Infant , Male , Pathological Conditions, Signs and Symptoms , Prune Belly Syndrome , Senegal
10.
Article in French | AIM | ID: biblio-1260253

ABSTRACT

Dans le but determiner les aspects épidémiologiques et anatomo-cliniques des cancers de l'estomac à Bamako, les auteurs ont entrepris une etude prospective transversal d'avril 2006 à décembre 2007 dans le Service de Gastroentérologie du CHU Gabriel Touré de Bamako et dans deux cliniques de la place. Au total 90 cas ont été diagnostiqués dont 62 hommes et 28 femmes (soit un sex ratio de 2,10). La moyenne d'âge était de 54,88 +/- 14,29 ans, avec des extrêmes de 18 et 85 ans. Les paysans et les ménagères ont été les plus atteints. Les manifestations cliniques les plus fréquentes étaient : l'épigastralgie (52,22 %), les vomissements (15,55 %) et l'amaigrissement (11,11 %). La localisation antrale (67,8 %), l'aspect ulcéro-bourgeonnant (61 %) et l'adénocarcinome bien différencié (37,8 %) sont les éléments caractéristiques de notre échantillon


Subject(s)
Mali , Pathological Conditions, Signs and Symptoms , Stomach Neoplasms/epidemiology , Stomach Neoplasms/pathology
11.
S. Afr. j. psychiatry (Online) ; 17(4): 118-120, 2011.
Article in English | AIM | ID: biblio-1270823

ABSTRACT

Objectives. Characteristics of children with autism spectrum disorders (ASDs) in Africa are not known because of unavailability of large-scale epidemiological studies in this region. This review explored the age at first presentation to orthodox clinical practice of African children with ASDs and their expressive language ability at presentation. Methods. A literature search of case series and case reports of ASDs from Africa was done through PubMed/MEDLINE, Google Scholar, African Journals Online (AJOL), and archives of the Nigerian Journal of Psychiatry. Six articles included content relating to age of the child at first presentation to orthodox clinical practice and symptoms at presentation related to expressive language ability and therefore fulfilled the inclusion criteria. Suggestions are made to explain the observations emanating from the review. Results. An excess of non-verbal over verbal cases of ASDs have been presenting to orthodox clinical practice and there is a common denominator of late presentation/diagnosis and in turn late intervention, with most cases presenting for the first time well above 8 years of age. Attempts to explain these observations included low levels of knowledge and awareness about ASDs in Africa, problems with help-seeking behaviour, and lack of mental healthcare facilities and trained personnel. nclusions. Enhancement of processes directed at ensuring early diagnosis and interventions, especially interventions aimed at improving speech and language development well and sufficiently early, may bring about a shift in the trend of excess non-verbal cases of ASDs over verbal cases presenting to orthodox clinical practice


Subject(s)
Child Development Disorders, Pervasive , Delayed Diagnosis , Diagnostic Techniques and Procedures , Disabled Children , Language Development Disorders , Language Disorders , Language Therapy , Pathological Conditions, Signs and Symptoms
12.
Afr. j. psychiatry rev. (Craighall) ; 13(5): 390-394, 2010. tab
Article in English | AIM | ID: biblio-1257868

ABSTRACT

Abstract Objective: Epidemiological studies indicate that methamphetamine (MA) abuse poses a major challenge to health in the Western Cape. The objectives of this study were to retrospectively assess the trends, clinical characteristics and treatment demand of MArelated admissions to a psychiatric ward in this region. Method: The clinical records of patients admitted to an acute psychiatric admission ward at Tygerberg Hospital from 1 January 2002 to 30 June 2002 and 1 January 2006 to 30 June 2006, were retrospectively reviewed. Admission numbers including those of adolescent and adult substance users were compared for both study periods. Study samples comparing demographic profile, admission status, length of stay, psychopathology, treatment requirements and referral pattern to other disciplines between MA users and non-users were collected for the 2006 period. Results: There was a significant (p <0.01) increase in adolescent substance user admissions between the study periods. A significant (p <0.01) increase in adolescent and adult MA user admissions was also noted. MA users were significantly (p = 0.04) younger than non-MA users, whilst the former presented mainly with psychotic features associated with aggression, requiring involuntary admission of an average of 8 weeks. MA users required significantly (p = 0.007) more benzodiazepines compared to non-MA users. Conclusion: Although MA use is relatively recent to the Western Cape, its adverse psychiatric effects and consequences have become a major challenge. These effects in both adolescent and adult patient populations and the associated impact on psychiatric services demand urgent intervention strategies as well as prospective study


Subject(s)
Methamphetamine , Pathological Conditions, Signs and Symptoms , Patient Admission , Psychiatric Department, Hospital , Review
13.
Afr. j. psychiatry rev. (Craighall) ; 11(2): 35-43, 2008. ilus
Article in English | AIM | ID: biblio-1257833

ABSTRACT

Abstract Objective: Depression will be the most common mental disorder by 2020, and it is also expected to be the second leading cause of disability, after cardiac diseases. Moreover, depression is likely to be a major public health burden in the future. This study evaluates the influences of culture on the symptoms of depression among Sesotho speakers. Method: An evaluation of a sample of 100 participants diagnosed with depression was conducted, using the Psychiatric Interview Questionnaire. Results: It was found that depression among Sesotho speakers is manifested in three areas: somatic symptoms, perceptual disturbances and disturbances of the thought processes. Conclusion: Since it has become clear, on the basis of the investigation, that depression is a culturally diverse phenomenon, the authors also recommend that research in this regard should be conducted from a multidisciplinary perspective, so that other paradigms, including those of sociology and anthropology, can also be included


Subject(s)
Culture , Depression , Pathological Conditions, Signs and Symptoms , South Africa
14.
Médecine Tropicale ; 68(3): 283-286, 2008.
Article in French | AIM | ID: biblio-1266828

ABSTRACT

Une étude rétrospective a été menée entre 1991 et 2003 afin de documenter le profil sémiologique et évolutif du lupus érythémateux systémique à Lomé. Nous avons recensé dans quatre services à Lomé 16 cas de lupus systémique, tous chez des femmes dont l'âge moyen était de 31,93 ans. Les manifestations cliniques les plus fréquentes étaient : les lésions de lupus discoïde (87,5%), le rash malaire (56,25%), l'alopécie (43,7%), les polyarthralgies (87,5%) et des sérites (37,5%). Les anomalies biologiques observées étaient : une anémie hémolytique (68,7%), une leucopénie (31,25%) et une protéinurie (37,5%). Les anticorps antinucléaires et les DNA natifs étaient présents respectivement dans 92,3% et 76,9%. La durée moyenne de suivi était de 33,56 mois. Les infections (68,7%) ont constitué les principales complications. Nous avons enregistré 5 cas de décès (31,25%) dont les causes étaient essentiellement iatrogènes


Subject(s)
Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/etiology , Lupus Erythematosus, Systemic/therapy , Pathological Conditions, Signs and Symptoms , Togo
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