ABSTRACT
Clinicopathologic correlation of skin biopsies is relevant in a dermatology patient's management. The study aimed to conduct a clinicopathologic corellation of skin samples. Methods: Retrospective cross-sectional analysis of 2,396 skin biopsy specimens submitted between January 2015 and December 2021. Clinicopathologic correlation was done on only samples which had definitive clinical and histopathologic diagnosis. Data was analyzed with the R studio. Results: A total number of 2,396 skin biopsies were received from 2319 patients. Clinicopathologic correlation was conducted on 1,831 samples which had both definitive clinical and histopathological diagnoses. A definitive clinicopathologic correlation was obtained in 66.8% (1224/1831) and this was 64.8% for benign tumours, 60.4% for malignant tumours, 66.7% for inflammatory diseases, 70.8% for infections, 85.5% for scalp and hair disorders and 50% for dermal deposits. Conclusion: Clinicopathologic correlation of skin biopsies is high. Correlation is better with inflammatory diseases compared to neoplastic diseases
Subject(s)
Humans , Skin Diseases , Neoplasm, Residual , Skin , Cross-Sectional Studies , Pelvic Inflammatory Disease , Correlation of DataABSTRACT
Background: Gynecological emergencies which affect the adolescents may pose a serious challenge to both the patient and the gynecologist. Objectives: The objective of this study is to determine the clinical presentations and management outcomes of emergency adolescent gynecological disorders at Federal Teaching Hospital, Abakaliki. Materials and Methods: This is a retrospective review of all cases of adolescent gynecological emergencies managed at Federal Teaching Hospital Abakaliki between January 1, 2012, and December 31, 2014. Data obtained from their case notes were analyzed using the IBM statistics version 20 (IBM Corp., Armonk, NY, USA). Data were presented using percentages and pie chart. Results: The prevalence of adolescent gynecological emergency disorders was 5.1%. The majority (82%) of the patients belong to the age bracket 1519 with a mean age of 16.7 (2.4) years. About 90% of the patients were nulliparous. Unmarried patients comprised 80% of the study group. Vaginal bleeding was the most common clinical presentation (86%). The two most common diagnoses were abortion (60%) and sexual assault (26%). Only 10% of sexually active adolescent were using any form of contraception. Care received includes manual vaccum aspiration, laparotomy, and antibiotics. Blood transfusion was given in 18% of the cases. No death was recorded in all the cases. Conclusion: Abortive conditions and sexual assault were the most common clinical diagnosis among adolescents in the study. The percentage of adolescent assaulted in our study is unacceptable and should be prevented and efforts should be made to reduce the high unmet need for contraception seen in the study
Subject(s)
Abortion , Contraception , Emergencies , Gynecological Examination , Hemorrhage , Lakes , Nigeria , Pelvic Inflammatory DiseaseABSTRACT
Background: Pelvic inflammatory disease refers to any infection in the female lower reproductive tract that spreads to the upper reproductive tract. The disease comprises a spectrum of inflammatory disorders of the upper female genital tract; including any combination of endometritis; salpingitis; tubo-ovarian abscess and pelvic peritonitis. PID is not a notifiable disease in most countries; so accurate statistics are not available. This situation is not in any way different here in Nigeria and more so in the Federal Capital Territory; Abuja where this research was conducted; there had never been any published report so far on PID. It therefore became pertinent that such studies be carried out to evaluate the bacterial organisms which may be associated with the disease in this part of Nigeria so that health care providers could take a better look at this affliction in women. Materials and Methods: Endocervical swabs totalling 100 were aseptically collected from patients with confirmed Pelvic Inflammatory Disease (PID); attending some hospitals in Abuja; Nigeria for detection of bacterial pathogens based on cultural and biochemical characterisation tests. Antibiogram was also conducted on the identified bacterial isolates. Results: Out of the 100 samples analysed; 43 yielded pure cultures of bacterial isolates; 2 yielded mixed cultures while no bacterial growths were recorded from the remaining 55 samples. Organisms encountered were Staphylococcus aureus (16); Escherichia coli (10); Streptococcus faecalis (8); Pseudomonas aeruginosa (4); Streptococcus pyogenes (3); Klebsiella pneumoniae (3); Proteus rettgeri (2) and Proteus mirabilis (1). The highest percentage occurrence of pathogenic isolates was observed in polygamous married patients (90). The age group most affected falls within the mean age 30.5 years (68) while the least affected group falls within the mean age 40.5 years (5). There was a significant difference in the acquisition of PID in relation to marital status (P 0.05). However there was no significant difference in the acquisition of the disease with respect to age (P 0.05). Antibiogram patterns of pathogenic isolates revealed varied resistance to most of the antibiotics employed. Cefotaxime (a new generation cephalosporin antibiotic) was established in this study as the best antimicrobial agent for treatment of PID due to Gram-positive and Gram-negative bacteria isolated from the women examined. Conclusion: In conclusion; Pelvic inflammatory disease is a major health problem in developed or developing countries of the world. PID is not a notifiable disease; as accurate statistics on disease prevalence are rarely available. There is therefore no doubt thousands of young women have salpingitis every year and their sheer number makes it an important health problem. PID hence can be said to be a very serious complication of sexually transmitted disease which should be critically and promptly handled by healthcare providers. The right type sample should be aseptically collected and be appropriately handled for laboratory investigation. Treatment of PID should be initiated as soon as the presumptive diagnosis has been made. Immediate administration of antibiotics has been effective in the long-term sequelae associated with PID; especially new generation antibiotics; such as cefotaxime as recorded in this study
Subject(s)
Nigeria , Pelvic Inflammatory Disease , Reproductive Tract InfectionsABSTRACT
La Mission Medicale Chinoise travaille a la Clinique Bon Secours; annexe du C.H.U. Tokoin de Lome depuis 21 ans. Une statistique des consultations dans le service de Gynecologie sur la periode allant de janvier 1988 a janvier 1995 donne un nombre total de malades consultees egal a 31.102. Parmi les affections frequemment diagnostiquees; la pelvite vient en tete avec 9.984 cas; soit 32.10 pour cent. La sterilite essentiellement provoquee par l'obstruction des trompes dues a la pelvite; vient en seconde position avec 6.784 cas (soit 27;83 pour cent) dont 6.140 cas (19;74 pour cent) sont dus a l'obstruction des trompes consecutive a la pelvite. La pelvite et les maladies resultant d'elle representent ainsi 51;84 pour cent du total sus mentionne. C'est donc une maladie frequente; menacant gravement la sante des Togolaises
Subject(s)
Infertility , Infertility/etiology , Pelvic Inflammatory Disease/epidemiologyABSTRACT
Les infections gynecologiques hautes sont dues a des germes varies; aerobies et anaerobies; mais souvent associees aux maladies sexuellement transmissibles. Le Chlamydia Trachomatis est plus frequemment retrouve que le gonocoque et le mycoplasme. La plupart des auteurs proposent une association d'antibiotiques: amoxicilline - acide clavulanique plus cycline; cephalosporine de 2eme et 3eme generation plus metronidazole et cycline; clindamycine et une cycline; et recemment; l'association ofloxacine et anoxicilline - acide clavulanique parait tres efficace. Le traitement anti-inflammatoire permet d'eviter les sequelles; et la coelioscopie garde sa place en cas d'abces