First documented case of Devic's neuromyelitis optica in Niger

Devic's neuromyelitis optica is a chronic inflammatory demyelinating disease of the central nervous system that mainly affects spinal cord, optic nerve and brain regions with high aquaporin 4 antigen expression. We report the first documented case of Devic's neuromyelitis optica in Niger. It was a 66-year-old black man who had presented a rapidly progressive flaccid tetraplegia associated with vesico-sphincteral disorders, in whom magnetic resonance imaging had shown longitudinally extensive transverse cervical myelitis with positive anti-NMO antibodies

Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a Case Report and Literature Review

Background : Locked-in syndrome is an extremely difficult neurologic condition to recognize; especially by the non-specialists. A case of locked-in syndrome in a 41-year old Niger Deltan Nigerian with relapsing remitting form of multiple sclerosis (MS) is presented; including a detailed literature review. Patient and Case Report The patient was in a state of spastic quadriplegia; motionless and aphasic (mute); with the preservation of consciousness and the ability to open and blink the eyes and move them vertically. Two episodes of the disease; varying in duration; have been described. The diagnosis of MS was made from the history and the typical clinical presentation: history of relapsing and remitting signs and clinical evidence of multi-focal involvement of the central nervous system. Conclusion Patient died at the age of 45 years; from pulmonary complications. This article may enhance easy recognition and management of the syndrome by all clinicians

Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a Case Report and Literature Review

Background : Locked-in syndrome is an extremely difficult neurologic condition to recognize; especially by the non-specialists. A case of locked-in syndrome in a 41-year old Niger Deltan Nigerian with relapsing remitting form of multiple sclerosis (MS) is presented; including a detailed literature review. Patient and Case Report The patient was in a state of spastic quadriplegia; motionless and aphasic (mute); with the preservation of consciousness and the ability to open and blink the eyes and move them vertically. Two episodes of the disease; varying in duration; have been described. The diagnosis of MS was made from the history and the typical clinical presentation: history of relapsing and remitting signs and clinical evidence of multi-focal involvement of the central nervous system. Conclusion Patient died at the age of 45 years; from pulmonary complications. This article may enhance easy recognition and management of the syndrome by all clinicians