ABSTRACT
Background: psoriatic arthritis (PsA) is a chronic, inflammatory, progressive joint disease. It has much psychosocial impact and affects quality of life (QOL) of the patients. Aim of the study: to determine the psychosocial impact of PsA on the patients and to define QOL of them. Patients and Methods: the study was conducted on 50 PsA patients, 68 psoriasis (Ps) patients, and 100 controls. A case-control, clinic-based study design was used in this research. An interviewing form and Middle Sex Hospital Questionnaire were used to survey the characteristics of the patients and controls. Severity of PsA was determined clinically. Also, the medical outcomes study 36-item short form (SF-36) was used to assess impact of the disease on the patient's QOL. Results: most (92.0%) of PsA patients had psychiatric symptoms. The disease had interfered with most of patients' personal feelings and relationships, daily activities, school/work, and leisure/sport. Majority (88.0%) of the patients had stigma feeling. Also, 40.0% and 60.0% of PsA patients had severe and mild forms, respectively. The differences between two forms of PsA regarding interference with school/work and presence of suicidal ideation were significant. The difference regarding presence of familial psychological stress was significant. The highly affected SF-36 domain scores were general health and physical limitation. The eight mean domain scores were significantly lower among PsA patients than controls. The mean domain scores of physical functioning, physical limitation, social functioning, emotional limitation, and mental health were significantly lower among patients with severe PsA than those with mild PsA. The eight mean domain scores were significantly lower among PsA patients than those with only Ps. Conclusions: the physical and psychosocial aspects of PsA may interact and influence one another. So, PsA has a great effect on the patients' QOL; disrupting physical and psychosocial aspects, and interfering with daily activities, school/work, and leisure/sport. QOL scores were significantly lower among PsA than only Ps patients
Subject(s)
Adult , Egypt , Quality of Life/psychologyABSTRACT
Introduction: Psychiatric illness is common among patients with chronic disorders; particularly in those with end-stage renal disease on renal replacement therapy (RRT). Patients with a functioning renal allograft have an improved quality of life (QOL) compared to patients on dialysis. Objective: to evaluate the psychological disorders and QOL among dialysis patients and renal transplant recipients. Patients and Methods: This is a prospective cross-sectional study that included 168 patients on RRT. Their psychological health status was assessed through clinical examination and relevant designed questionnaires .The data obtained were fed to the SPSS for analysis. Significance was assumed at P 0.05. Results: Out of 168 ESRD Sudanese patients; 43 (25.6) received renal allograft. The frequency of depression was 90 (72) and nine (25.6) of patients on dialysis; and kidney transplant recipients respectively. Anxiety was reported with significant difference (p 0.001) in the dialyzed patients compared to kidney transplant recipients. Sleep disorders were experienced by 81 (64.8) of dialyzed; and nine (20.9) of kidney transplant recipients (P0.001). Conclusion: Psychological disorders in dialyzed ESRD patients have significant effect on the quality of life and may have a tremendous impact on mortality and morbidity. For this reason; supportive management by psychologist and or psychiatrist is recommended for early detection and alleviation of symptoms of mood and mind disturbances. For most patients with ESRD kidney transplantation offers the greatest potential for restoring healthy productive life