Diagnostic d'orientation et traitement des cancers thyroidiens au Mali

Notre objectif a ete de rapporter les criteres de diagnostic d'orientation des cancers de la thyroide dans les conditions de la pratique en zone sahelienne. Ce travail s'etait base surl'analyse de dossiers de 29 personnes porteurs de cancer de la thyroide; vus dans le serice d'Oto-Rhino-Laryngologie (ORL) de l'hopital Gabriel Toure de Bamako au Mali; de janvier 2002 a decembre 2007. Trois symptomes ont constitue le motif de consultation : tumefaction cervicale dure (21 as) evoluant depuis plus de 10 ans; presence de signes de compression (dysphonie :5 cas; dyspnee :3; dysphasie : 1) et des adenopathies cervicales (6 cas). La confirmation histologique du diagnostic a ete faite par analyse du produit cytoponction ou d'une piece operatoire. Le traitement majeur a ete le geste chirurgical dont l'analyse de la piece operatoire a permis de connaitre le diagnostic positif. L'orientation diagnostique pre-therapeutique a montre ainsi sa place preponderante dans un contexte d'absence d'exonne extemporane

Thyroid Cancers amongst Goiter Population in a Nigerian Tertiary Hospital:Surgical and Radiographic Perspective

Background: Goiters are commonly benign; but cases of malignancy can develop. Thyroid cancer is known to be commoner in whites than in blacks and in females than in males. Bone metastasis is a common occurrence and may be the initial manifestation in a small subset. We hope to determine the incidence and the cervical radiographic patterns of thyroid cancer amongst goiter population in Nigeria. Method: Surgical; histological and radiographic findings in patients with goiter who had thyroidectomy in our hospital from 1999 to 2006 were reviewed.Those with proven cancer were analyzed for sex; age and radiographic changes using SPSS 11.0 for windows. Results Thirteen (8.2) cases out of the 160 goiters were malignant and distant metastases were present in 1.3at presentation. The histological sub-types of malignant goiters were follicular (5.0); papillary (1.9) and poorly differentiated or anaplastic thyroid carcinoma (1.3). As much as 30of thyroid cancers demonstrated calcification on plain neck radiograph; which were commonly scattered or diffused. Conclusions: Carcinomatous goiters occurred in 9.3of the goiter population studied with predominance of follicular variant. Surgery remains the main stay but was inappropriate in about 1.2of population with goitre. Aside evidence of bony destruction; TC should be suspected in goiters with mixed (diffused or scattered) calcifications