ABSTRACT
Sleeping sickness is often considered a disease of adults rather than children due to their reduced exposure to the vector. Presumptive diagnosis of sleeping sickness was however difficult since the clinical signs observed were non-specific. This makes clinical diagnosis difficult. Often the disease in children masquerades as a pulmonary infection that is undetectable on x-ray or auscultation. A male child aged two years and eight months was diagnosed with the disease in western Kenya. The patient presented with severe respiratory distress; hepatosplenomegay and neurological symptoms. The disease transmission was associated with the socio-cultural habit of placing children under bushes whilst farming. The implications of delayed diagnosis on response to treatment are discussed
Subject(s)
Case Reports , Child , Trypanosomiasis , Trypanosomiasis/therapy , Trypanosomiasis/transmissionABSTRACT
The pyrethroid insecticide lambda-cyhalothrin was evaluated in field trials against Glossina f.fuscipes and sleeping sickness transmission in Iyolwa sub-county; Tororo District; Uganda. The insecticide was applied selectively to the resting-sites of tsetse; by bush-spraying; using 10pc wettable powder (10WP) formulation at an application rate of 11.6 g a.i./ha over an area of 28 km2; or by a 2pc Electrodyn formulation (2ED) applied at 0.9 g a.i./ha over 30 km2. In a third trial area of 32 km2; 215 pyramidal traps treated with lambda-cyhalothrin 100 mg/m2 were set. The best impact was obtained with 10WP lambda-cyhalothrin which eliminated tsetse within 1-2 months; whereas G.f.fuscipes persisted at very low density in part of the area treated with 2ED lambda-cyhalothrin. In both treated areas the numbers of human sleeping sickness cases fell to no more than one per month; compared with four to twelve per month previously. The overall rate of cattle trypanosomiasis (T.brucei and T.vivax) was also reduced slightly. Insecticide-treated traps remained fully effective for at least 6 months under field conditions and catches were reduced 20-90-fold. These results in the control of tsetse and trypanosomiasis transmission lead us to recommend lambda-cyhalothrin for tsetse control operations