ABSTRACT
BACKGROUND: The aim of this study was to assess the role of transabdominal ultrasonography in characterizing and determining the etiology of ascites in comparison with laboratory ascitic fluid analysis and other methods used to establish the final diagnosis. METHODS: A prospective descriptive study was conducted on 61 patients with ascites attending outpatient department (OPD) or admitted to wards of Tikur Anbesa Specialized Hospital (TASH) and referred to radiology department for imaging from June 2017 to November 2017. Data were collected following the internationally recommended scanning technique in consecutive bases. The data were analyzed using SPSS version 20. The comparison of ultrasound and laboratory findings with final clinical diagnosis was analyzed using Chi-square test (X2). RESULTS: Of 61 patients with ascites enrolled in this study, females were 35(57.4%) with age range of 16 to 75 and mean age of 43.2±14.11. The cause of ascites was established in 59 cases using a combination of clinical, pathological, imaging evidences and tumor markers. However there were two cases who had ascites with indeterminate cause. US suggested the diagnosis in 54(91.5%) patients. Excluding mixed and indeterminate cases, ultrasound characterized ascites correctly as exudate and transudate in 95% cases. CONCLUSION: Ultrasound has significant accuracy to distinguish transudate and exudate ascites and in suggesting the underlying cause. It can be a valuable method of investigation of ascites in places where CT and MRI are not available, and it is the best complement for laboratory investigations on ascites in suggesting the etiology based on ascitic fluid texture and ancillary findings
Subject(s)
Ascites/diagnosis , Ascites/etiology , Ethiopia , Outpatients , Patients , UltrasonographyABSTRACT
Introduction : Les ascites métastatiques cancéreuses sont caractérisées par la présence de cellules cancéreuses métastatiques dans le liquide péritonéal. Elles sont fréquentes à un stade avancé des cancers. Il s'agissait de déterminer la contribution de la cytologie au diagnostic et à l'évaluation du pronostic des ascites métastatiques dans le service d'Anatomie et Cytologie Pathologiques du CHU du Point G. Matériel et méthode : Notre étude s'est étendue de Janvier 2013 à Décembre 2015; soit une période de 3 ans. Elle était rétrospective et prospective incluant tous les patients dont l'étude cytologique des liquides d'ascitea mis en évidence des cellules malignes. Le dossier médical des patients a été exploité pour la recherche du site primitif et du diagnostic histologique éventuel et le suivi. Résultats : Sur 213 examens cytologiques de liquide d'ascite; 61 étaient malins, soit un taux de 28,64%. La tranche d'âge la plus répresentée était de 46 à 60 ans avec un âge moyen de 53,7 ± 14,7 ans. Le sexe féminin était dominant avec un taux de 66%. La profession la plus fréquente était les ménagères soit un taux de 50,82%. Le siège primitif le plus fréquent était l'ovaire (26%). Il était suivi par le foie et l'estomac avec respectivement 20% et 18%. L'ascite a été le signe révélateur du cancer dans 36% des cas. Elle était isolée dans 78%. Après 6 mois de suivi, le taux de mortalité était 75,6%. Conclusion : L'examen cytologique constitue un examen paraclinique dans le diagnoticdes ascites métastatiques cancéreuses
Subject(s)
Ascites/diagnosis , Ascitic Fluid , Cell Biology , Mali , Neoplasms , PrognosisABSTRACT
Background: Ascites is always a feature of an underlying disease; whose cause is unknown at presentation most of the time. Its initial treatment therefore will be empirical and dependent on the most frequent and common causes in the environment. Aim: To evaluate a cohort of patients with ascites to determine the common causes in the University of Port Harcourt Teaching Hospital (UPTH). Methods: We undertook a clinical evaluation of 96 consecutive cases seen at the UPTH; over a three-year period; using a combination of diagnostic modalities which included biochemical; serological and cytological examination of the ascitic fluid; as well as radiology and ultrasonography; and histological examinations of liver biopsy specimens in cases suggestive of liver disease. Results: The three most common causes of ascites in this series were liver diseases-36.5(chronic liver disease 27.1; hepatocellular carcinoma 9.4); renal diseases 30.2(chronic renal failure 23.9; nephrotic syndrome 6.3); and cardiac diseases 23.9(congestive cardiac failure 22.9; Endomyocardial fibrosis 1). The clinical conditions associated with portal hypertension (liver and cardiac diseases) accounted for 60of cases. Localized intra-abdominal disease; such as tuberculosis was rare (3.1); and chronic alcohol consumption was very common amongst all aetiological groups. Peripheral oedema was a frequent accompaniment of the renal and cardiac cases more than the liver diseases; whereas pleural effusion was very rare. Conclusion: Patients presenting with ascites can be commenced on diuretics and salt restriction pending the establishment of a definitive diagnosis
Subject(s)
Ascites/diagnosis , Ascites/etiology , Ascites/therapyABSTRACT
Si du point de vue semiologie; syndrome ascitique est aujourd'hui clairement defini; il persiste encore des problemes etiologiques et meme therapeutiques. L'examen clinique; la ponction exploratrice; l'echographie et la laparoscopie constituent neanmoins les elements fondamentaux qui permettent de deblayer le terrain
Subject(s)
Ascites/diagnosis , Ascites/etiologyABSTRACT
Si du point de vue semiologique; le syndrome ascitique est aujourd'hui clairement defini; il persiste encore des problemes etiologiques et meme therapeutiques. L'examen clinique; la ponction exploratrice; l'echographie et la laparascopie constituent neanmoins des elements fondamentaux qui permettent de deblayer le terrain