"Hyperlipidemia in ""A"" blood group African subjects"

ABSTRACT

"Atherosclerosis is known to be related to hypercholesterolemia and ""ABO"" blood group in non African adults. This study was undertaken to determine if such a correlation between high lipid fractions and ABO blood groups also exists in African population. Two hundred and two subjects were used in this study 36.5 per cent of them belonged to the A blood group.; 14.8 per cent to the B blood group; 2 per to the AB blood group and 46.7 per cent to the O blood group. Blood group A subjects were found to be having high total cholesterol and ApoB level and a slight increase of LDL.C Level. Analysis of the variance showed that the cholesterol level of blood group A persons was significantly different from blood group B. ApoB level of blood group A subjects was significantly different from blood B or O. When separated into two sexes; there was no significant difference between the cholestrerol level of A blood group female and male; and between their ApoB level. Elevated level of cholesterol associated in blood group A persons with high ApoB level and high ApoB/ApoA1 ratio over 0.65 enable the authors to conclude that these persons belonged to a high cardiovascular risk group; and this disease could be prevented by an early diet management"