Bacteriology of Diabetic Foot Ulcers in Bacteriology; in Benin City; Nigeria

ABSTRACT

This study aimed to determine the bacteriological pattern and antimicrobial susceptibility of diabetic foot ulcer (DFU) infections seen in our practice; with a view to suggesting optimal therapy for these patients. Forty-seven persons with DFU were seen. The mean age was 56 years. Of these; 30 (64) had wound swabs sent for bacteriological assessment and antibiotic sensitivity patterns. There were 20 non-gangrenous ulcers and 10 gangrenous ulcers. Proteus spp and coliform organisms were the most predominantly isolated organisms in gangrenous ulcers; while Staphylococcus aureus; coliforms; and Pseudomonas aeruginosa were commonly isolated in non-gangrenous ulcers. Grampositive organisms were sensitive to ciprofloxacin (100); gentamicin (100); and perfloxacin (88). Gram-negative organisms were sensitive to ciprofloxacin (74); gentamicin (43); and perfloxacin (39). We conclude that ciprofloxacin and gentamicin are the most effective antibiotics against gram-positive and gram-negative organisms; and thus recommend the combination of ciprofloxacin and/or gentamicin and metronidazole as initial therapy for patients with infected DFU while awaiting culture results: