The effect of levamisole chemotherapy on geohelminthiasis among children aged 6-12 years - Freetown; Sierra Leone

ABSTRACT

The therapeutic effect of levamisole (ketrax) in 28 children aged 6-12 years old living in Freetown; Sierra Leone against ascaris lumbricoides; hookworm and trichuris trichiura infections was investigated. Levamisole effectively reduced the intensity of all three infections. Prevalence returned more rapidly to pre-treatment levels than did intensity. A lumbricoides was found to be the most sensitive to the drug followed by hookworm. Although prevalence of T. trichiura rose by day 56 in each course there was reduction in eggs per gram of stool (e.p.g.). There were no side effects reported throughout the study