Insulin Resistance Induced by Antiretroviral Drugs: Current Understanding of Molecular Mechanisms
JEMDSA (Online)
; 14(3): 129-132, 2010.
Article
in English
| AIM
| ID: biblio-1263736
Responsible library:
CG1.1
ABSTRACT
The increase in incidence of HIV infection continues to be a major public health problem across the world; but more especially in sub- Saharan Africa. Treatment with highly active antiretroviral therapy (HAART) has improved the prognosis of patients with AIDS; but it has also increased the incidence of various metabolic disorders; in particular insulin resistance accompanied by dyslipidaemia; hyperglycaemia and lipodystrophy. This is often accompanied by frank type 2 diabetes and increased mortality from cardiovascular disease. It is important to understand the mechanistic basis for these side-effects as the incidence of these is likely to increase as the rollout of antiretroviral drugs continues
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Index:
AIM (Africa)
Main subject:
Insulin Resistance
/
HIV Protease Inhibitors
/
Anti-Retroviral Agents
Language:
English
Journal:
JEMDSA (Online)
Year:
2010
Type:
Article
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