Effects of some storage conditions on the stability of hydrocortisone sodium succinate injections
Journal of Pharmacetuical and Allied Sciences
; 3(1): 269-280, 2005.
Article
in English
| AIM
| ID: biblio-1264457
Responsible library:
CG1.1
ABSTRACT
In this study; the effects of some environmental storage conditions -light; temperature and humidity on the stability of the steroidal drug; hydrocortisone sodium succinate injection were investigated. The drug samples were stored at varying conditions of light; temperature (0OC; 28OC and 60OC) and humidity; after which each sample was assayed at weekly intervals for their content of the drug using a UV -Vis spectrophotometer. From the results obtained; storage under light; at enhanced temperature and in the presence of moisture had pronounced degradative effects on the stability of hydrocortisone sodium succinate injection; calling for caution in the storage of this widely used anti-allergic and anti-inflammatory drug
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Index:
AIM (Africa)
Main subject:
Hydrocortisone
/
Drug Stability
/
Drug Storage
/
Injections
Language:
English
Journal:
Journal of Pharmacetuical and Allied Sciences
Year:
2005
Type:
Article
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