Clinical and laboratory characteristics of HIV-1 infection in Zimbabwe
Journal of acquired immune deficiency syndromes
; 3(7): 701-707, 1990.
Article
in English
| AIM
| ID: biblio-1264528
Responsible library:
CG1.1
ABSTRACT
To define the impact of human immunolodeficiency virus (HIV) infection in Africa; clinical and laboratory investigations were conducted on 265 HIV-seropositive outpatients in Zimbabwe. Twenty-four of the study subjects were asymptomatic (ASX); 124 had persistent generalized lympademopathy (PGL); and 117 had AIDS-related complex (ARC). HIV infection was assessed by commercial ELISA; Western blots; synthetic peptide ELISA; and measurement of p24 antigen. Serum immunoglobulins; lympocyte mitogen responses; and CD4+ cell numbers were obrtained in 54 sequential patients. Compared to seronegative subjects meab CD4+ cell numbers were decreased and serum immunoglobulins; particularly IgM and IgG; were increased in all groups of seropositive subjects. [abstract terminated]
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Index:
AIM (Africa)
Main subject:
AIDS Serodiagnosis
/
HIV Infections
Language:
English
Journal:
Journal of acquired immune deficiency syndromes
Year:
1990
Type:
Article
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