Circurating trypanosomal antigen levels in sleeping sickness patients under going treatment at Alupe
Proceedings of the KEMRI/KETRI Annual Medical Scientific Conference
; 13(2): 139-143, 1992.
Article
in English
| AIM
| ID: biblio-1268805
Responsible library:
CG1.1
ABSTRACT
Sera from 99 sleeping sickness patients admitted to Alupe Hospital were analyzed for circulating trypanosomal antigens using a sandwich antigen-trapping enzyme immunosorbent assay. Trypanosomal antigens were detected in 83 (84) of the patients. Post-treatment antigen profile in 67 patients showed five distinct patterns in 48 of the patients antigen levels remained elevated thoughout; in 31 of the patients antigens dropped to the; negative value; and became elevated afterward; in 6.0 of the patients antigen levels were negative initially; but became elevated later; in 7.5 of the patients antigen levels remained below the negative value thoughout. The significance of these observations in the clinical management of sleeping sickness is discussed
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Index:
AIM (Africa)
Main subject:
Trypanosomiasis
/
Antigens
Language:
English
Journal:
KETRI Annual Medical Scientific Conference
Year:
1992
Type:
Article
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