Antibiotic Synergy Profiles of Multidrug-Resistant - Pseudomonas aeruginosa in a Nosocomial Environment
S. Afr. j. infect. dis. (Online)
; 23(3): 7-9, 2008.
Article
in English
| AIM
| ID: biblio-1270593
Responsible library:
CG1.1
ABSTRACT
Pseudomonas aeruginosa is one of the most common nosocomial pathogens in intensive care units (ICUs); with an increased prevalence of multidrug resistance in nosocomial infections. This study aimed to determine antibiotic synergy profiles of multidrugresistantP. aeruginosa originating from ICU patients in a teaching hospital in Pretoria; South Africa. Susceptibility studies and in vitrosynergy testing were performed; utilising agar dilution and Etest methodology; respectively. Susceptibility studies revealed 94of isolates exhibiting resistance to more than three anti-pseudomonal agents tested. Results from antibiotic synergy studies suggested that cefepime (p0.0001) or meropenem (p0.0001) in combination with amikacin are possible treatment options available in this specific setting:
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Index:
AIM (Africa)
Main subject:
Pseudomonas aeruginosa
/
Drug Resistance
/
Cross Infection
/
Anti-Bacterial Agents
Type of study:
Risk factors
Language:
English
Journal:
S. Afr. j. infect. dis. (Online)
Year:
2008
Type:
Article
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